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Evaluation of the effects of supplementation with brown and golden flax (Linum usitatissimum L.) flour on lipid profile and weight gain in Wistar rats

In this work, the effects of brown and golden flax flour were compared based on lipid profile and weight gain in Wistar rats. The animals were randomly divided into three groups: control group (CG); group supplemented with brown flax flour (BF); and group supplemented with golden flax flour (GF). The animals were subjected to weight assessment on alternate days until sacrifice at the 36th day, when blood samples were collected for lipid profile evaluation. The use of flax flour as dietary supplement to Wistar rats, in a 35-day period, led to a significant decrease in the serum levels of triglycerides and TC:HDL-C ratio, with concomitant increase in HDL-C serum levels, demonstrating thus a cardioprotective effect. The effects on rat weight gain over the experimental period suggest an important preventive action of flax flour on the obesity development.

brown flax flour; golden flax flour; lipid profile; body weight; Wistar rats


Sociedade Brasileira de Plantas Medicinais Sociedade Brasileira de Plantas Medicinais, Revista Brasileira de Plantas Medicinais, Universidade Estadual de Maringá, Departamento de Farmácia, Bloco T22, Avenida Colombo, 5790, 87020-900 - Maringá - PR, Tel: +55-44-3011-4627 - Botucatu - SP - Brazil
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