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Microbiological control of medicinal drugs commercialized in the central region of Rio Grande do Sul, Brazil

The aim of this study was to analyze the microbiological quality of 40 samples of raw material for herbal medicines collected from compounding pharmacies in the center of Rio Grande do Sul, Brazil. Count of viable microorganisms and search and identification of pathogens were performed, both according to the Brazilian Pharmacopoeia. Results showed that there were microorganisms in the samples; however, in none of them, the value of CFU g-1 was above the limit established for herbal medicines by the British Pharmacopoeia, both for bacteria and fungi. The search and identification of pathogens indicated that there was no Pseudomonas aeruginosa, Salmonella sp, Staphylococcus aureus and Escherichia coli in the analyzed samples. The samples can be commercialized because all of them were within the allowed limits and were approved in the test for microbiological quality control.

microbiological quality control; compounding pharmacy; medicinal plants


Sociedade Brasileira de Plantas Medicinais Sociedade Brasileira de Plantas Medicinais, Revista Brasileira de Plantas Medicinais, Universidade Estadual de Maringá, Departamento de Farmácia, Bloco T22, Avenida Colombo, 5790, 87020-900 - Maringá - PR, Tel: +55-44-3011-4627 - Botucatu - SP - Brazil
E-mail: revista@sbpmed.org.br