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Pamidronate treatment in SAPHO syndrome

Although relatively rare and still not frequently diagnosed, SAPHO syndrome has specific features that originated the acronym: Synovitis, Acne, Pustulosis, Hyperostosis and Osteitis. Diagnosis is made possible through a combination of clinical manifestations, laboratory findings, and radiological exams, with bone scintigraphy playing a prominent role. Pamidronate is a second-generation bisphosphonate that affects bone turnover and exhibits anti-inflammatory properties, being a treatment option for this entity. With this case report, we aim to draw attention to SAPHO syndrome and the use of Pamidronate for its treatment.

SAPHO; scintigraphy; pamidronate


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