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APACHE IV score in postoperative kidney transplantation

ABSTRACT

Objectives:

To evaluate the calibration and discrimination of APACHE IV in the postoperative period after kidney transplantation.

Methods:

This clinical cohort study included 986 hospitalized adult patients in the immediate postoperative period after kidney transplantation, in a single center in southern Brazil.

Results:

Kidney transplant patients who died in hospital had significantly higher APACHE IV values and higher predicted mortality. The APACHE IV score showed adequate calibration (H-L 11.24 p = 0.188) and a good discrimination ROC curve of 0.738 (95%CI 0.643 - 0.833, p < 0.001), although SMR overestimated mortality (SMR = 0.73; 95%CI: 0.24 - 1.42, p = 0.664).

Conclusions:

The APACHE IV score showed adequate performance for predicting hospital outcomes in the postoperative period for kidney transplant recipients.

Keywords:
Kidney transplantation; APACHE IV; Validation studies; Prognosis

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