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Research on Biomedical Engineering, Volume: 34, Número: 1, Publicado: 2018
  • Neuro-behavioral pattern of sleep bruxism in wakefulness Original Article

    Azevedo, Marila Rezende; Sena, Ronaldo; Freitas, Amanda Medeiros de; Silva, Andrei Nakagawa; Lamounier Júnior, Edgard Afonso; Soares, Alcimar Barbosa

    Resumo em Inglês:

    AbstractIntroduction: Sleep Bruxism (SB) is a non-functional rhythmic movement of the mandible with multifactorial aetiology and complex diagnose. It has been the subject of various studies over the past decades and it is considered a result of actions of the Central Nervous System modulated by Autonomous Nervous System. In this work, we test the hypothesis that SB subjects present a typical and defined neurobehavioral pattern that can be distinct from that of non-bruxers subjects and can be measured during wakefulness. Methods Fifteen sleep bruxers (experimental-group EG) and fifteen non-bruxers (control-group CG) took part in the experiments. To verify the presence and severity of SB, clinical examinations, anamneses and questionnaires, including Visual Analogic Scale - faces (VAS-f) and State-Trait Anxiety Inventory (STAI) were applied. To legitimate the diagnoses of SB, a disposable instrument (Bitestrip®) to assess the masseter activity during sleep was employed. All subjects were submitted to a set of experiments for measuring various visual evoked responses during the presentation of visual stimuli (pleasant, unpleasant and neutral images). Events in Visual Evoked Potential (VEP) were used to compare the neural responses of both CG and EG. Results VAS-f showed EG with higher perception of stress than CG (trait: p=0.05), and lower quality of life for (state: p=0.007). STAI I and II showed significant differences of anxiety between CG and EG (p=0.013 and p=0.004, respectively), being EG the highest. The EG Bitestrip scores confirmed that 100% of subjects were sleep bruxers. Significant differences were found between EG and CG for events associated with emotional (pleasant and unpleasant) images in the first 250 ms after stimulation. In general, EG subjects showed higher amplitude and shorter latency of VEP events. Conclusion It is possible to distinguish between SB and non-bruxers subjects during wakefulness, based on differences in amplitude and latency of cortical event related potentials elicited by visual stimulation. SB subjects show greater amplitudes in specific events in frontal areas when non-pleasant images are shown. Latencies tend to be anticipated in SB compared to CG subjects.
  • Kinematic and electromyographic analysis of school children gait with and without load in the backpack Original Article

    Jorge, Jéssica Garcia; Faria, Amanda Nascimento de; Furtado, Daniel Antônio; Pereira, Adriano Alves; Carvalho, Eliane Maria de; Dionísio, Valdeci Carlos

    Resumo em Inglês:

    AbstractIntroduction: Excessive load on the backpacks can lead to musculoskeletal injuries and gait alterations. The objective of this study was to analyze the electromyographic (EMG) activity in association to the kinematic during the stance and balance phases of gait performed with and without the use of the backpack. Methods Twelve volunteers have executed a gait cycle in 3 tasks: without the school backpack (SM), with a backpack with load equivalent to 10% (M10) and 20% (M20) of the body weight (BW). It was evaluated the ankle, knee and hip angular excursion (AE), linear displacement (LD) of the toe and ankle, knee, hip, shoulder, head and EMG activity of the tibialis anterior (TA), vastus medialis (VM), rectus abdominis (RA), gastrocnemius lateral (GL), biceps femoris (BF) and spinal erector (EE) muscles. Results In the LD in the stance phase there was an AP increase for the toe and ankle, hip and head (p<0.043). In the balance phase for VT (vertical) direction, the shoulder presented a smaller displacement as well as the toe, ankle, knee, hip, shoulder and head in the ML direction. In the AP direction, the toe displacement was smaller as well as the ankle (p < 0.038). The AE in both phases was smaller for the hip (p <0.006). In the balance phase the IEMG was higher for the RA (p = 0.034). Conclusion These results suggest that the transport of school backpacks with loads of more than 10%BW causes changes in the kinematic and in the muscular recruitment pattern.
  • AD-SISCOLO: a decision-support tool to aid the management of a cervical cancer screening program Original Article

    Ahmed, Sulafa Yacoub Mohammed; Freire, Sergio Miranda; Feitosa, Tereza Maria Piccinini; Zardo, Lucilia Maria Gama; Almeida, Rosimary Terezinha de

    Resumo em Inglês:

    AbstractIntroduction: This paper aims to develop a data warehouse (AD-SISCOLO) in order to support the management of the cervical cancer screening program in the municipality of Rio de Janeiro/Brazil. As a part of the management process, the program managers of the municipality perform tedious manual work in order to calculate a series of performance indicators and then take decisions based on them. Methods AD-SISCOLO was implemented using the Pentaho BI Suite Business Intelligence Platform and the MySQL database management system. The indicators to be calculated and visualized in the tool were based on the municipal data of the cytopathology and histopathology tests from January 2012 until December 2014, which was obtained from the Information System of Cervical Cancer (SISCOLO) after a record linkage process. The follow-up indicators were based on a simplified version of the Brazilian guidelines for the cervical cancer screening. Results AD-SISCOLO allows the visualization of a set of test-based and follow-up indicators from different views and dimensions, which enable managers to monitor all the phases of the screening process and to identify the process’ failures. Conclusions Compared with the current available environments in Brazil, AD-SISCOLO is unique in its visualization of the follow-up indicators of groups of women, according to their test results and age. Thereby it provides presentation flexibility to suit the program manager's needs.
  • Absorbed doses in salivary and thyroid glands from panoramic radiography and cone beam computed tomography Original Article

    Heiden, Katia Regina; Rocha, Anna Silvia Penteado Setti da; Filipov, Danielle; Salazar, Cristina Berrocal; Fernandes, Ângela; Westphalen, Fernando Henrique; Setti, João Antonio Palma

    Resumo em Inglês:

    Abstract Introduction: Panoramic radiography and cone beam computed tomography (CBCT) are very important in the diagnosis of oral diseases, however patients are exposed to the risk of ionizing radiation. This paper describes our study aimed at comparing absorbed doses in the salivary glands and thyroid due to panoramic radiography and CBCT and estimating radiation induced cancer risk associated with those methods. Methods Absorbed doses of two CBCT equipment (i-CAT® Next Generation and SCANORA® 3D) and a digital panoramic device (ORTHOPANTOMOGRAPH® OP200D) were measured using thermoluminescent dosimeters loaded in an anthropomorphic phantom on sublingual, submandibular, parotid and thyroid glands. Results Absorbed doses in the i-CAT® device ranged between 0.02 (+/-0.01) and 2.23 mGy (+/-0.03), in the SCANORA™ device ranged from 0.01 (+/-0.01) to 2.96 mGy (+/-0.29) and in the ORTHOPANTOMOGRAPH® OP200D ranged between 0.04 mGy and 0.78 mGy. The radiation induced cancer risk was highlighted in the salivary glands, which received higher doses. The protocols that offer the highest risk of cancer are the high resolution protocols of CBCT equipment. Conclusion CBCT exposes patients to higher levels of radiation than panoramic radiography, so the risks and benefits of each method should be considered. The doses in CBCT were dependent on equipment and exposure parameters, therefore adequate selection minimizes the radiation dose.
  • Compensation technique for environmental and light source power variations applied in a polymer optical fiber curvature sensor for wearable devices Original Article

    Leal-Junior, Arnaldo Gomes; Frizera, Anselmo; Pontes, Maria José

    Resumo em Inglês:

    Abstract Introduction Polymer optical fibers (POF) are lightweight, present high elastic strain limits, fracture toughness, flexibility in bend, and are not influenced by electromagnetic fields. These characteristics enable the application of POF as curvature sensor and can overcome the limitations of the conventional technologies, especially for wearable and soft robotics devices. Nevertheless, POF based curvature sensors can suffer from environmental and light source power deviations. This paper presents a compensation technique for the environmental and light source power deviations in a POF curvature sensor. Methods The curvature sensor was submitted to variations of temperature, humidity and light source power to characterize the sensor response and evaluate the proposed compensation technique. In addition, tests with the simultaneous variation of the angle and light source power variation were performed. Results Results show that temperature and humidity effects do not lead to significative errors on the sensor measurement for wearable devices application, where a hardware-based compact and portable compensation technique of the light source deviation is applied. Moreover, the sensor with the compensation technique developed is compared with a potentiometer for dynamic measurements and the root-mean-square error of about 1° is obtained, which is lower than sensors based on similar operation principle presented in the literature and some commercially available devices. Conclusions The compensation technique proposed was able to compensate power deviations applied and resulted in a sensor with low errors with the additional advantages of compactness and low-cost, which enable its application as wearable sensors and on the instrumentation of wearable robots.
  • Breast cancer diagnosis based on mammary thermography and extreme learning machines Original Article

    Santana, Maíra Araújo de; Pereira, Jessiane Mônica Silva; Silva, Fabrício Lucimar da; Lima, Nigel Mendes de; Sousa, Felipe Nunes de; Arruda, Guilherme Max Silva de; Lima, Rita de Cássia Fernandes de; Silva, Washington Wagner Azevedo da; Santos, Wellington Pinheiro dos

    Resumo em Inglês:

    Abstract Introduction Breast cancer is the most common cancer in women and one of the major causes of death from cancer among female around the world. The early detection and treatment are the major way to healing. The use of mammary thermography in Mastology is increasing as a complementary imaging technique to early detect lesions. Its use as a screening exam to identify breast disorders has been investigated. The aim of this study is to investigate the behavior of different classification methods while grouping the thermographic images into specific types of lesions. Methods To evaluate our proposal, we built classifiers based on artificial neural networks, decision trees, Bayesian classifiers, and Haralick and Zernike attributes. The image database is composed by thermographic images acquired at the University Hospital of the Federal University of Pernambuco. These images are clinically classified into the classes cyst, malignant and benign. Moments of Zernike and Haralick were used as attributes. Results Extreme Learning Machines (ELM) and Multilayer Perceptron networks (MLP) proved to be quite efficient classifiers for classification of breast lesions in thermographic images. Using 75% of the database for training, the maximum value obtained for accuracy was 73.38%, with a Kappa index of 0.6007. This result indicated to a sensitivity of 78% and specificity of 88%. The overall efficiency of the system was 83%. Conclusion ELM showed to be a promising classifier to be used in the differentiation of breast lesions in thermographic images, due to its low computational cost and robustness.
  • Finite element simulation of fracture in a restored premolar tooth using high aspect ratio elements Original Article

    Ramezani, Maryam; Las Casas, Estevam Barbosa de; Mattos, Cláudia Machado de Almeida; Manzoli, Osvaldo Luís; Rodrigues, Eduardo Alexandre

    Resumo em Inglês:

    Abstract Introduction The term cracked tooth syndrome refers to an incomplete fracture of a vital posterior tooth that involves the dentin and occasionally extends into the pulp. There is a very limited number of publications trying to model dentin crack growth using numerical techniques. Therefore, it is essential to numerically model this phenomenon in order to improve the clinical procedures. Methods A 2D finite element model is proposed to simulate crack initiation and propagation in a restored premolar tooth. The geometric model was based on computed tomography data. A special finite element technique, named mesh fragmentation technique, is used to model and analyze the behavior of the tooth. This technique was used to model cracks in quasi-brittle materials based on the use of interface solid finite elements with high aspects ratio. A tension damage constitutive relation between stresses and strains consistent with the continuous strong discontinuity approach is used to describe crack formation and propagation. Results The main aspects of modeling technique and procedures are explained in detail as well as the whole results, including both elastic and fracture analyses of the restored tooth. Conclusion The results of the current fracture analysis show that, under various loading conditions, there is no crack initiation in the restored tooth under typical loading magnitude. However, in the case of tooth with a pre-existing crack, which can be aroused during the restoration process, a crack propagation was observed, while they did not reach a critical fracture state.
  • Gait variability and symmetry assessment with inertial sensors for quantitative discrimination of Trendelenburg sign in total hip arthroplasty patients: a pilot study based on convenience sampling Original Article

    Ferreira, Luiz Cláudio Vieira; Rabelo, Amanda Gomes; Vieira, Marcus Fraga; Pereira, Adriano Alves; Andrade, Adriano de Oliveira

    Resumo em Inglês:

    Abstract Introduction The aim of this pilot study based on convenience sampling was to analyze the feasibility to quantitatively discriminate Trendelenburg sign (TS), a characteristic drop in pelvic position during gait in hip disfunctions, in patients with total hip arthroplasty (THA), by assessing gait variability and symmetry using inertial sensors. Methods Thirteen patients with right THA, divided into two groups with (GTS, n=4) and without TS (GnTS, n=9) assessed by experienced physician, were enrolled in the study. Harris Hip Score was applied for specific evaluation of THA. The protocol consisted in walking on a level treadmill during 3 minutes with two inertial sensors attached at anterior superior iliac spine of both sides. For each left and right step, features were extracted from the Y-axis gyroscope signals: peak value, mean absolute value, standard deviation and range. For each feature, a symmetry ratio was calculated as the ratio between left and right side. Results No significant differences were found in Harris Hip Score between groups. The variability assessed by standard deviation for left step, contralateral to the replaced side, was significantly larger for GTS group (p<0.001). Significant differences in the symmetry ratios were found between GTS and GnTS for all features extracted from gyroscopes Y-axis (W=144, p<0.001). The symmetry ratios for GnTS group were approximately equal one (except for range), whereas for the GTS group they exceed the 10% criterion. Conclusion The variability and symmetry ratios of gait features extracted from inertial sensors were successful to discriminate TS in THA patients.
  • A wavelet-based method for power-line interference removal in ECG signals Original Article

    Oliveira, Bruno Rodrigues de; Duarte, Marco Aparecido Queiroz; Abreu, Caio Cesar Enside de; Vieira Filho, Jozue

    Resumo em Inglês:

    Abstract Introduction The analysis of electrocardiogram (ECG) signals allows the experts to diagnosis several cardiac disorders. However, the accuracy of such diagnostic depends on the signals quality. In this paper it is proposed a simple method for power-line interference (PLI) removal based on the wavelet decomposition, without the use of thresholding techniques. Methods This method consists in identifying the ECG and noise frequency range for further zeroing wavelet detail coefficients in the subbands with no ECG coefficients in the frequency content. Afterward, the enhanced ECG signal is obtained by the inverse discrete wavelet transform (IDWT). In order to choose the wavelet function, several experiments were performed with synthetic signals with worse Signal-to-Noise Ratio (SNR). Results Considering the relative error metrics and runtime, the best wavelet function for denoising was Symlet 8. Twenty synthetic ECG signals with different features and eight real ECG signals, obtained in the Physionet Challenge 2011, were used in the experiments. Results show the advantage of the proposed method against thresholding and notch filter techniques, considering classical metrics of assessment. The proposed method performed better for 75% of the synthetic signals and for 100% of the real signals considering most of the evaluation measures, when compared with a thresholding technique. In comparison with the notch filter, the proposed method is better for all signals. Conclusion The proposed method can be used for PLI removal in ECG signals with superior performance than thresholding and notch filter techniques. Also, it can be applied for high frequencies denoising even without a priori frequencies knowledge.
  • Modeling and FPGA-based implementation of an efficient and simple envelope detector using a Hilbert Transform FIR filter for ultrasound imaging applications Technical Communication

    Assef, Amauri Amorin; Ferreira, Breno Mendes; Maia, Joaquim Miguel; Costa, Eduardo Tavares

    Resumo em Inglês:

    Abstract Introduction Although the envelope detection is a widely used method in medical ultrasound (US) imaging to demodulate the amplitude of the received echo signal before any back-end processing, novel hardware-based approaches have been proposed for reducing its computational cost and complexity. In this paper, we present the modeling and FPGA implementation of an efficient envelope detector based on a Hilbert Transform (HT) approximation for US imaging applications. Method The proposed model exploits both the symmetry and the alternating zero-valued coefficients of a HT finite impulse response (FIR) filter to generate the in-phase and quadrature components that are necessary for the envelope computation. The hardware design was synthesized for a Stratix IV FPGA, by using the Simulink and the integrated DSP Builder toolbox, and implemented on a Terasic DE4-230 board. The accuracy of our algorithm was evaluated by the normalized root mean square error (NRMSE) cost function in comparison with the conventional method based on the absolute value of the discrete-time analytic signal via FFT. Results An excellent agreement was achieved between the theoretical simulations with the experimental result. The NRMSE was 0.42% and the overall FPGA utilization was less than 1.5%. Additionally, the proposed envelope detector is capable of generating envelope data at every FPGA clock cycle after 19 (0.48 µs) cycles of latency. Conclusion The presented results corroborate the simplicity, flexibility and efficiency of our model for generating US envelope data in real-time, while reducing the hardware cost by up to 75%.
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