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Increase in Guillain-Barré syndrome hospitalizations in Brazil: an ecological study* * Article derived from the Master’s Degree dissertation entitled “Guillain-Barré syndrome hospitalization trend in Brazil, 2008-2017’, defended by Juliane Maria Alves Siqueira Malta at the University of Brasília (UnB) Postgraduate Tropical Medicine Program in 2019.

Abstract

Objective

to describe the demographic characteristics and the spatio-temporal dynamics of Guillain-Barré syndrome (GBS) hospitalizations in Brazil between 2008 and 2017.

Methods

this is an ecological study using data from the Hospital Information System of the Brazilian National Health System (SIH/SUS); GBS hospitalization rates were calculated and a control diagram was built; natural break ranges were used in the spatial analysis.

Results

15,512 GBS hospitalizations were recorded during the study period; between 2008-2014 there were 1,344 hospitalizations per year on average, in the following year (2015), 1,953 hospitalizations were registered, representing an increase of 45% in relation to the average of previous years; GBS hospitalizations reached an epidemic level in the Northeast region in 2015 and 2016.

Conclusion

GBS hospitalizations increased with effect from 2015, following the introduction of chikungunya virus and the rapid spread of Zika virus in Brazil.

Guillain-Barre Syndrome; Hospitalization; Epidemiology; Brazilian National Health System; Ecological Studies

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