BRIEF COMMUNICATIONS • Rev. Inst. Med. Trop. São Paulo 57 (2) • Mar-Apr 2015 • https://doi.org/10.1590/S0036-46652015000200011   copy

ANTIFUNGAL ACTIVITY OF SILVER NANOPARTICLES OBTAINED BY GREEN SYNTHESIS

Atividade antifúngica de nanopartículas de prata obtidas por síntese verde

Eduardo José J. MALLMANN Francisco Afrânio CUNHA Bruno N.M.F. CASTRO Auberson Martins MACIEL Everardo Albuquerque MENEZES Pierre Basílio Almeida FECHINE About the authors

Silver nanoparticles (AgNPs) are metal structures at the nanoscale. AgNPs have exhibited antimicrobial activities against fungi and bacteria; however synthesis of AgNPs can generate toxic waste during the reaction process. Accordingly, new routes using non-toxic compounds have been researched. The proposal of the present study was to synthesize AgNPs using ribose as a reducing agent and sodium dodecyl sulfate (SDS) as a stabilizer. The antifungal activity of these particles against C. albicans and C. tropicalis was also evaluated. Stable nanoparticles 12.5 ± 4.9 nm (mean ± SD) in size were obtained, which showed high activity against Candida spp. and could represent an alternative for fungal infection treatment.

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