Aerobic bacteria, Chlamydia trachomatis, Pneumocystis carinii and Cytomegalovirus as agents of severe peneumonia in small infants

Bactérias aeróbias, Chlamydia trachomatis, Pneumocystis carinii e Cytomegalovirus: agentes causadores de pneumonia grave em pequenos lactentes

Bernardo Ejzenberg Heloisa Melles Carmo Melles Rosa Dias Evandro Roberto Baldacci Yassuhiko Okay About the authors

Abstracts

The authors studied 58 infants hospitalized for pneumonia in a semi-intensive care unit. Age ranged from 1 complete to 6 incomplete months. The infants were sent from another hospital in 20 cases and from home in a further 38. Pulmonary involvement, which was alveolar in 46 cases and interstitial in 12, was bilateral in 31 children. The investigation was carried out prospectively on the etiological agents associated with respiratory infection to look for evidence of aerobic bacteria (blood cultures), Chlamydia trachomatis and Cytomegalovirus (serology), and Pneumocystis carinii (direct microscopy of tracheal aspirated material). The following infectious agents were diagnosed in 21 children (36.2%): Aerobic bacteria (8), Chlamydia trachomatis (5), Pneumocystis carinii (3), Cytomegalovirus (3), Cytomegalovirus and Chlamydia trachomatis (1), Aerobic bacteria and Cytomegalovirus (1). Seven cases of infection by Chlamydia trachomatis and/or Cytomegalovirus were diagnosed out of the 12 cases with pulmonary interstitial involvement.

Pneumonia; Etiology; Infant


Os autores estudaram prospectivamente 58 lactentes internados por pneumonia em unidade semi-intensiva. A idade foi limitada entre 1 mês completo e 6 meses incompletos. A procedência das crianças foi de outro hospital em 20 casos e domiciliar em 38. O acometimento pulmonar era alveolar em 46 casos, intersticial em 12 e bilateral em 31 crianças. Foram pesquisados agentes etiológicos associados à infecção respiratória dos lactentes jovens: Bactérias aeróbias (Hemoculturas), Chlamydia trachomatis e Cytomegalovirus (sorologia), e Pneumocystis carinii (microscopia direta do aspirado traqueal). Foram diagnosticadas infecções em 21 crianças (36,2%): Bactérias aeróbias (8), Chlamydia trachomatis (5), Cytomegalovirus (3), Pneumocystis carinii (3), Cytomegalovirus e Chlamydia trachomatis (1), Bactéria aeróbia e Cytomegalovirus (1). Foram diagnosticadas 7 infecções por Chlamydia trachomatis e/ou Cytomegalovirus entre as 12 crianças com quadro intersticial


MICROBIOLOGY

Aerobic bacteria, Chlamydia trachomatis, Pneumocystis carinii and Cytomegalovirus as agents of severe peneumonia in small infants

Bactérias aeróbias, Chlamydia trachomatis, Pneumocystis carinii e Cytomegalovirus: agentes causadores de pneumonia grave em pequenos lactentes

Bernardo EjzenbergI; Heloisa MellesII; Carmo MellesII; Rosa DiasII; Evandro Roberto BaldacciIII; Yassuhiko OkayIV

IPhD, MD. Children's Institute of the Pediatrics Department of the School of Medicine of the University of São Paulo

IIAdolfo Lutz Institute Researcher. Adolfo Lutz Institute

IIIPhD, MD, Emergency Care Director. Children's Institute of the Pediatrics Department of the School of Medicine of the University of São Paulo

IVChairman of Pediatrics Department. Children's Institute of the Pediatrics Department of the School of Medicine of the University of São Paulo

Correspondence to

SUMMARY

The authors studied 58 infants hospitalized for pneumonia in a semi-intensive care unit. Age ranged from 1 complete to 6 incomplete months. The infants were sent from another hospital in 20 cases and from home in a further 38. Pulmonary involvement, which was alveolar in 46 cases and interstitial in 12, was bilateral in 31 children. The investigation was carried out prospectively on the etiological agents associated with respiratory infection to look for evidence of aerobic bacteria (blood cultures), Chlamydia trachomatis and Cytomegalovirus (serology), and Pneumocystis carinii (direct microscopy of tracheal aspirated material). The following infectious agents were diagnosed in 21 children (36.2%): Aerobic bacteria (8), Chlamydia trachomatis (5), Pneumocystis carinii (3), Cytomegalovirus (3), Cytomegalovirus and Chlamydia trachomatis (1), Aerobic bacteria and Cytomegalovirus (1). Seven cases of infection by Chlamydia trachomatis and/or Cytomegalovirus were diagnosed out of the 12 cases with pulmonary interstitial involvement.

Keywords: Pneumonia; Etiology; Infant.

RESUMO

Os autores estudaram prospectivamente 58 lactentes internados por pneumonia em unidade semi-intensiva. A idade foi limitada entre 1 mês completo e 6 meses incompletos. A procedência das crianças foi de outro hospital em 20 casos e domiciliar em 38. O acometimento pulmonar era alveolar em 46 casos, intersticial em 12 e bilateral em 31 crianças. Foram pesquisados agentes etiológicos associados à infecção respiratória dos lactentes jovens: Bactérias aeróbias (Hemoculturas), Chlamydia trachomatis e Cytomegalovirus (sorologia), e Pneumocystis carinii (microscopia direta do aspirado traqueal). Foram diagnosticadas infecções em 21 crianças (36,2%): Bactérias aeróbias (8), Chlamydia trachomatis (5), Cytomegalovirus (3), Pneumocystis carinii (3), Cytomegalovirus e Chlamydia trachomatis (1), Bactéria aeróbia e Cytomegalovirus (1). Foram diagnosticadas 7 infecções por Chlamydia trachomatis e/ou Cytomegalovirus entre as 12 crianças com quadro intersticial

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ACKNOWLEDGEMENTS

The authors thank Dr. Vera Lúcia Marão of the Immunology Laboratory of the School of Medicine of the University of São Paulo for carrying out serological tests for Cytomegalovirus.

  • Correspondence to:
    Dr. Bernardo Ejzenberg
    Av. Prof. Lineu Prestes, 2565
    Cidade Universitária - USP. 05508-900 São Paulo, SP, Brasil
  • Recebido para publicação em 11/09/1995.

    Aceito para publicação em 19/12/1995.

    Informed consent was obtained from the parents or guardians. The present investigation was carried out in accordance with the ethical norms approved for research by The Children's Institute of the Pediatrics Department of the School of Medicine of the University of São Paulo.

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    Correspondence to: Dr. Bernardo Ejzenberg Av. Prof. Lineu Prestes, 2565 Cidade Universitária - USP. 05508-900 São Paulo, SP, Brasil

    Publication Dates

    • Publication in this collection
      22 Sept 2006
    • Date of issue
      Feb 1996

    History

    • Accepted
      19 Dec 1995
    • Received
      11 Sept 1995
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