Neurocriptococose durante a gravidez: revisão da literatura. Relato de dois casos

Cryptococcal meningitis in pregnancy: review of the literature. Report of two cases

Resumos

São descritos os dois primeiros casos de neurocriptococose durante a gravidez diagnosticados em São Paulo (Brasil). Uma paciente foi tratada com anfotericina B no segundo trimestre, a outra, com anfotericina B no primeiro trimestre e no 2º trimestre com anfotericina B e 5 flucitosina. Ambas tiveram boa evolução materna e fetal. É apresentada revisão da literatura da neurocriptococose em gestantes.

Neurocriptococose; Gravidez; Anfotericina B; Flucitosina


Two cases of neurocryptococcosis were diagnosed during pregnancy in São Paulo (Brazil). Amphotericin B was used in the second trimester in one patient. The other, received amphotericin B during the first trimester of pregnancy and 5-fluorocytosine was added in the second trimester. In both, the pregnancy was uneventful and the fetus suffered no damage. The therapy used to treat pregnant women with cryptococcal meningitis is commented. The newborn follow-up is discussed. A review of the literature concerning neurocryptococcosis during pregnancy is presented.

Neurocriptococose; Gravidez; Anfotericina B; Flucitosina


REGISTRO DE CASO

Neurocriptococose durante a gravidez. Revisão da literatura. Relato de dois casos

Cryptococcal meningitis in pregnancy. Review of the literature. Report of two cases

Carlos Alberto Pires PereiraI; Olga FischmanII; Arnaldo Lopes ColomboI; Antonio Fernandes MoronIII; Antonio Carlos Campos PignatariI

IDisciplina de Doenças Infecciosas e Parasitárias da Escola Paulista de Medicina. São Paulo, SP, Brasil

IIDisciplina de Biologia Celular, Setor de 'Micologia Médica da Escola Paulista de Medicina. São Paulo, SP, Brasil

IIIDisciplina de Obstetrícia da Escola Paulista de Medicina. São Paulo, SP, Brasil

Endereço para correspondência

RESUMO

São descritos os dois primeiros casos de neurocriptococose durante a gravidez diagnosticados em São Paulo (Brasil). Uma paciente foi tratada com anfotericina B no segundo trimestre, a outra, com anfotericina B no primeiro trimestre e no 2º trimestre com anfotericina B e 5 flucitosina. Ambas tiveram boa evolução materna e fetal.

É apresentada revisão da literatura da neurocriptococose em gestantes.

Unitermos: Neurocriptococose; Gravidez; Anfotericina B; Flucitosina.

SUMMARY

Two cases of neurocryptococcosis were diagnosed during pregnancy in São Paulo (Brazil). Amphotericin B was used in the second trimester in one patient. The other, received amphotericin B during the first trimester of pregnancy and 5-fluorocytosine was added in the second trimester. In both, the pregnancy was uneventful and the fetus suffered no damage.

The therapy used to treat pregnant women with cryptococcal meningitis is commented. The newborn follow-up is discussed.

A review of the literature concerning neurocryptococcosis during pregnancy is presented.

Texto completo disponível apenas em PDF.

Full text available only in PDF format.

Recebido para publicação em 20/10/1992

Aceito para publicação em 21/12/1992

Trabalho realizado na Escola Paulista de Medicina - Hospital São Paulo. Rua Botucatú, 740 - Vila Clementino. São Paulo, SP, Brasil.

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  • Endereço para correspondência:
    Carlos Alberto Pires Pereira
    Rua Napoleão de Barros, 715 - 1º andar
    Vila Clementino. CEP 04023-062 São Paulo, SP, Brasil
    Fone: 572-6348, Fax: (011) 572-6348 ou 549-2127

Datas de Publicação

  • Publicação nesta coleção
    21 Jul 2006
  • Data do Fascículo
    Ago 1993

Histórico

  • Aceito
    21 Dez 1992
  • Recebido
    20 Out 1992
Instituto de Medicina Tropical de São Paulo Av. Dr. Enéas de Carvalho Aguiar, 470, 05403-000 - São Paulo - SP - Brazil, Tel. +55 11 3061-7005 - São Paulo - SP - Brazil
E-mail: revimtsp@usp.br