Use of MAC-ELISA for evaluation of yellow fever vaccination

Uso do MAC-ELISA para avaliação de vacinados contra febre amarela

Rita M. Ribeiro Nogueira Hermann G. Schatzmayr Marize P. Miagostovich Silvia M. B. Cavalcanti Ricardo de Carvalho About the authors

An evaluation of the IgM antibody immune response against yellow fever using strain 17D was carried out by MAC-ELISA and PRNT. The results showed an agreement of 97% between both tests and the authors conclude that MAC-ELISA can be used as a specific and sensitive asssay to replace the PRNT for detecting yellow fever antibodies in human sera, after vaccination programs.

Yellow fever vaccinated; MAC-ELISA; PRNT


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