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Nosocomial Infections • Rev. Inst. Med. Trop. Sao Paulo 56 (1) • Jan-Feb 2014 • https://doi.org/10.1590/S0036-46652014000100010   copy

FIRST REPORT OF METALLO-β-LACTAMASES PRODUCING Enterobacter spp. STRAINS FROM VENEZUELA

Primer reporte de cepas de Enterobacter spp productoras de metalobetalactamasas de Venezuela

Authorship SCIMAGO INSTITUTIONS RANKINGS

Clinical strains of Enterobacter were isolated from Cumana's Central Hospital in Venezuela, and classified as E. cloacae (21), E. aerogenes(7), E. intermedium (1), E. sakazakii (1) and three unclassified. The strains showed high levels of resistance, especially to SXT (58.1%), CRO (48.8%), CAZ (46.6%), PIP (46.4%), CIP (45.2%) and ATM (43.3%). This is the first report for South America of blaVIM-2 in two E. cloacae and one Enterobacter sp., which also showed multiple mechanisms of resistance. Both E. cloacaeshowed blaTEM-1, but only one showed blaCTX-M-15 gene, while no blaSHV was detected.

Carbapenemase; Metallobetalactamase; VIM; Enterobacter ; Carbapenems

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