Relationship between acute malaria and anti-resa antibodies in sera of patients from two different endemic areas in Brazil

Malafronte, Rosely dos S.; Valdivia, Jorge Luis; Miranda, Antonio de; Kloetzel, Judith K.

doi:10.1590/S0036-46651994000400010

RESA/Pf155; P. falciparum; Acute malaria

SHORT COMMUNICATION

Relationship between acute malaria and anti-resa antibodies in sera of patients from two different endemic areas in Brazil

Rosely dos S. Malafronte^I; Jorge Luis Valdivia^II; Antonio de Miranda^III; Judith K. Kloetzel^I,IV

^IInstituto de Medicina Tropical de São Paulo; São Paulo, S.P., Brasil

^IICompanhia Florestal de Monte Dourado

^IIIEscola Paulista de Medicina

^IVInstituto de Ciências Biomédicas, Depto. de Parasitologia

^{Correspondence to} Correspondence to: R. S. Malafronte I. M. T. S. P. Av. Dr. Enéas de Carvalho Aguiar, 470 CEP: 05403-000, São Paulo, S P, Brasil

Keywords: RESA/Pf155; P. falciparum; Acute malaria.

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ACKNOWLEDGEMENTS

Supported by Companhia Florestal de Monte Dourado (C.F.M.D.), CNPq-Conselho Nacional de Desenvolvimento Científico e Tecnológico and Laboratórios de Investigação Médica do Hospital das Clínicas. We thank Fundação Nacional da Saúde (Pará) for local logistic support and Dr. C.E. Tosta - Universidade de Brasília for the original strain of P.falciparum. Skillful technical assistance of Angela M. Lourenço and Regina A. de Paula is acknowledged.

Recebido para publicação em 08/10/1993

Aceito para publicação em 12/05/1994.

1. BERZINS, K; PERLMANN, H; WAHLIN, B. et al. - Rabbit and human antibodies to a repeated amino acid sequence of a Plasmodium falciparum antigen, Pf155, react with the native protein and inhibit merozoite invasion. Proc. nat. Acad. Sci. (Wash.), 83: 1065-1069, 1986.
2. BJORKMAN, A.; PERLMANN, H.; PETERSEN, E. et al. - Consecutive determinations of seroreactivities to Pfl55/RESA antigen and to its different repetitive sequences in adult men from a holoendemic area of Liberia. Paras. Immunol., 12: 115-123, 1990.
3. CHIZZOLINI, C.; DUPONT, A.; AKUE, J.P. et al. - Natural antibodies against three distinct and defined antigens of Plasmodium falciparum in residents of a mesoendemic area in Gabon. Amer. J. trop. Med. Hyg., 39: 150-156, 1988.
4. CHUMPITAZI, B.F.F.; DELORON, P.; PEYRON, F. et al. - Relationships between clinical protection and antibodies to Plasmodium falciparum RESA (ring-infected erythrocyte surface antigen) peptides. Int. J. Parasit., 21: 271-274, 1991.
5. FAVAROLO, J.M.; COPPEL, R.L.; CORCORAN, L.M. et al. - Structure of the RESA gene of Plasmodium falciparum. Nucleic Acids Res., 14: 8265-8277, 1986.
6. HOLDER, A.A. ; LOCKYER, M.J.; ODINK, K.G. et al. - Primary structure of the precursor to the three major surface antigens of Plasmodium falciparum merozoites. Nature, 317: 270-273, 1985.
7. KLOETZEL, J.K.; MALAFRONTE, R.S.; GONDO, S. & NOGUEIRA, M.C.L. - Anti-RESA (Pfl55) antibodies in malaria patients from Pará and Rondônia, Brazil. Ann. trop. Med. Parasit., 84: 531-533, 1990.
8. MALAFRONTE, R.S.; VALDIVIA, J.L.; NAKAIE, C. & KLOETZEL, J.K. - Seasonal variation of anti-RESA (Pf155) Plasmodium falciparum antibodies in three localities from the State of Amapá, Brazil. Rev. Inst. Med. trop. S.Paulo, 36: 237-243, 1994.
9. PERLMANN, H.; BERZINS, K; WAHLGREN, M. et al. - Antibodies in malarial sera to parasite antigens in the membrane of erythrocytes infected with early asexual stages of Plasmodium falciparum J. exp. Med., 159: 1686-1704, 1984.
10. PETERSEN, E.; HOGH, B.; PERLMANN, H. et al. - An epidemiological study of humoral and cell-mediated immune responses to the Plasmodium falciparum antigen Pf155/RESA in adult Liberians. Amer. J. trop. Med. Hyg., 41: 386-394, 1989.

Correspondence to:

R. S. Malafronte

I. M. T. S. P.

Av. Dr. Enéas de Carvalho Aguiar, 470

CEP: 05403-000, São Paulo, S P, Brasil

Publication Dates

Publication in this collection
20 Sept 2006
Date of issue
Aug 1994

History

Accepted
12 May 1994
Received
08 Oct 1993

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

[1] 1. BERZINS, K; PERLMANN, H; WAHLIN, B. et al. - Rabbit and human antibodies to a repeated amino acid sequence of a Plasmodium falciparum antigen, Pf155, react with the native protein and inhibit merozoite invasion. Proc. nat. Acad. Sci. (Wash.), 83: 1065-1069, 1986.

[2] 2. BJORKMAN, A.; PERLMANN, H.; PETERSEN, E. et al. - Consecutive determinations of seroreactivities to Pfl55/RESA antigen and to its different repetitive sequences in adult men from a holoendemic area of Liberia. Paras. Immunol., 12: 115-123, 1990.

[3] 3. CHIZZOLINI, C.; DUPONT, A.; AKUE, J.P. et al. - Natural antibodies against three distinct and defined antigens of Plasmodium falciparum in residents of a mesoendemic area in Gabon. Amer. J. trop. Med. Hyg., 39: 150-156, 1988.

[4] 4. CHUMPITAZI, B.F.F.; DELORON, P.; PEYRON, F. et al. - Relationships between clinical protection and antibodies to Plasmodium falciparum RESA (ring-infected erythrocyte surface antigen) peptides. Int. J. Parasit., 21: 271-274, 1991.

[5] 5. FAVAROLO, J.M.; COPPEL, R.L.; CORCORAN, L.M. et al. - Structure of the RESA gene of Plasmodium falciparum. Nucleic Acids Res., 14: 8265-8277, 1986.

[6] 6. HOLDER, A.A. ; LOCKYER, M.J.; ODINK, K.G. et al. - Primary structure of the precursor to the three major surface antigens of Plasmodium falciparum merozoites. Nature, 317: 270-273, 1985.

[7] 7. KLOETZEL, J.K.; MALAFRONTE, R.S.; GONDO, S. & NOGUEIRA, M.C.L. - Anti-RESA (Pfl55) antibodies in malaria patients from Pará and Rondônia, Brazil. Ann. trop. Med. Parasit., 84: 531-533, 1990.

[8] 8. MALAFRONTE, R.S.; VALDIVIA, J.L.; NAKAIE, C. & KLOETZEL, J.K. - Seasonal variation of anti-RESA (Pf155) Plasmodium falciparum antibodies in three localities from the State of Amapá, Brazil. Rev. Inst. Med. trop. S.Paulo, 36: 237-243, 1994.

[9] 9. PERLMANN, H.; BERZINS, K; WAHLGREN, M. et al. - Antibodies in malarial sera to parasite antigens in the membrane of erythrocytes infected with early asexual stages of Plasmodium falciparum J. exp. Med., 159: 1686-1704, 1984.

[10] 10. PETERSEN, E.; HOGH, B.; PERLMANN, H. et al. - An epidemiological study of humoral and cell-mediated immune responses to the Plasmodium falciparum antigen Pf155/RESA in adult Liberians. Amer. J. trop. Med. Hyg., 41: 386-394, 1989.