Prevalence of HTLV-I antibody among two distinct ethnic groups inhabiting the Amazon region of Brazil

Prevalência do anticorpo HTLV-I em dois grupos étnicos distintos habitando a região da Amazônia Brasileira

Abstracts

HTLV-I seroprevalences of 3.63% (02/55), 12.19% (10/82) and 13.88% (10/72) were demonstrated among Tiryio, Mekranoiti and Xicrin Amazonian Indians, respectively, by the Western blotting enzyme assay (WBEI). By indirect immuno electron microscopy (IIEM), 2 Tiriyo, 9 Mekranoiti and 6 Xicrin Amerindians were reactive. Of 44 serum samples from Japanese immigrants, none reacted by any of the techniques before mentioned. One, 8 and 6 serum samples from Tiryio, Mekranoiti and Xicrin Indians, respectively, were both WBEI and IIEM positive. Our results strongly suggest that HTLV-I and/or an HTLV-I antigenic variant circulate (s) among populations living in the Amazon region of Brazil.

Human T-lymphotropic virus type I (HTLV-I); Amazonian Indians; Amerindians; Japanese Immigrants


Soroprevalências para HTLV-I de 3,63% (02/55), 12,9% (10/82) e 13,88% (10/72) foram demonstradas entre os Tiryió, Mekranoiti e Xicrin, respectivamente - indígenas habitantes da Amazônia -, utilizando-se a técnica de "Western Blot" (WBEI). Por outro lado, a imunomicroscopia eletrônica indireta (IIME) revelou como positivos 2 Tiryió, 9 Mekranoiti e 6 Xicrins. Das 44 amostras de soro oriundas de migrantes japoneses, nenhuma resultou positiva pelas duas técnicas antes mencionadas. Foram reativos por ambos os métodos, 1, 8 e 6 amostras dos índios Tiryió, Mekranoiti e Xicrin, respectivamente. Nossos resultados representam uma forte evidência de que o HTV-I e/ou variante(s) antigenicamente similar(es) circula(m) entre populações que habitam a região amazônica do Brasil.


EPIDEMIOLOGY

Prevalence of HTLV-I antibody among two distinct ethnic groups inhabiting the Amazon region of Brazil

Prevalência do anticorpo HTLV-I em dois grupos étnicos distintos habitando a região da Amazônia Brasileira

C.M. NakauchiI; Koshi MaruyamaII; L.I. KanzakiIII; A.C. LinharesI; V.N. AzevedoIII; T. FukushimaII; M. MiyauchiII; N. KoshikawaII; C. TamayamaII; S. MochizukiII; K. KawamuraII

IInstituto Evandro Chagas, Fundação Nacional de Saúde, Belém, Pará, Brasil

IIChiba Cancer Research Institute, Chiba, Japan

IIIUniversidade Federal do Pará, Depto. de Patologia, Laboratório de Virologia

Address for correspondence

SUMMARY

HTLV-I seroprevalences of 3.63% (02/55), 12.19% (10/82) and 13.88% (10/72) were demonstrated among Tiryio, Mekranoiti and Xicrin Amazonian Indians, respectively, by the Western blotting enzyme assay (WBEI). By indirect immuno electron microscopy (IIEM), 2 Tiriyo, 9 Mekranoiti and 6 Xicrin Amerindians were reactive. Of 44 serum samples from Japanese immigrants, none reacted by any of the techniques before mentioned. One, 8 and 6 serum samples from Tiryio, Mekranoiti and Xicrin Indians, respectively, were both WBEI and IIEM positive. Our results strongly suggest that HTLV-I and/or an HTLV-I antigenic variant circulate (s) among populations living in the Amazon region of Brazil.

Key words: Human T-lymphotropic virus type I (HTLV-I); Amazonian Indians; Amerindians; Japanese Immigrants.

RESUMO

Soroprevalências para HTLV-I de 3,63% (02/55), 12,9% (10/82) e 13,88% (10/72) foram demonstradas entre os Tiryió, Mekranoiti e Xicrin, respectivamente - indígenas habitantes da Amazônia -, utilizando-se a técnica de "Western Blot" (WBEI). Por outro lado, a imunomicroscopia eletrônica indireta (IIME) revelou como positivos 2 Tiryió, 9 Mekranoiti e 6 Xicrins. Das 44 amostras de soro oriundas de migrantes japoneses, nenhuma resultou positiva pelas duas técnicas antes mencionadas. Foram reativos por ambos os métodos, 1, 8 e 6 amostras dos índios Tiryió, Mekranoiti e Xicrin, respectivamente. Nossos resultados representam uma forte evidência de que o HTV-I e/ou variante(s) antigenicamente similar(es) circula(m) entre populações que habitam a região amazônica do Brasil.

Full text available only in PDF format.

Texto completo disponível apenas em PDF.

ACKNOWLEDGEMENTS

We are indebted to JICA staff for their kindness in the transportation of specimens. Thanks are due to Mr. Francisco T. Pantaleão and Mr. Antonio de Moura for technical advice.

Recebido para publicação em 24/10/1991

Aceito para publicação em 26/06/1992

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  • Address for correspondence:
    Dr. A.C. Linhares
    Instituto Evandro Chagas
    Av. Almirante Barroso, 492
    66.065, Belém, Pará, Brasil

Publication Dates

  • Publication in this collection
    12 Sept 2006
  • Date of issue
    Aug 1992

History

  • Received
    24 Oct 1991
  • Accepted
    26 June 1992
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