Enzyme-linked immunosorbent assay for the detection of IgM antibodies in human leptospirosis

An enzyme-linked immunosorbent assay (ELISA) for the detection of immunoglobulin M (IgM) antibodies in human leptospirosis was evaluated. From the results obtained in this study, it may concluded that the IgM-ELISA is a suitable technique not only for the detection of low levels of antibody, but also for measurement of non-agglutinating antibodies undetectable by means of microscopic agglutination test.

Instituto de Medicina Tropical de São Paulo Av. Dr. Enéas de Carvalho Aguiar, 470, 05403-000 - São Paulo - SP - Brazil, Tel. +55 11 3061-7005 - São Paulo - SP - Brazil
E-mail: revimtsp@usp.br