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Mycobacterial subcutaneous arteritis

Arterite subcutânea por micobactéria

Abstracts

The authors report three patients with subcutaneous erythematous nodules in different phases of development, inespecific systemic symptoms, positive PPD test, and normal chest X-rays. The histopathological study of the older nodules showed a granulomatous arteritis with a few acid-fast bacilli in the vascular wall. The nodules at an early phase showed an inespecific panniculitis with some acid-fast bacilli in apparently normal cutaneous vessels. These findings suggest that the mycobacterium has a vascular tropism and may cause a primary granulomatous arteritis.

Erythema induratum Bazin; Erythema nodosum; Vasculitis


Os autores descrevem três casos de pacientes com nódulos subcutâneos em diferentes fases de evolução, com sintomas sistêmicos inespe-cíficos, PPD positivo e raio-X de tórax normal. O estudo anátomo-patológico dos nódulos antigos mostrou arterite granulomatosa e com raros bacilos álcool-ácido resistentes na parede vascular; os nódulos recentes mostraram paniculite inespecífica com alguns bacilos álcool-ácido resistentes na parede de vasos cutâneos aparentemente normais. Esses achados sugerem que a micobactéria tem um tropismo vascular e pode causar arterite granulomatosa.


ORIGINAL ARTICLES

Mycobacterial subcutaneous arteritis

Arterite subcutânea por micobactéria

Consuelo Junqueira Rodrigues; Fernando Peixoto Ferraz de Campos; Lais Lage Furtado-Mendonça; Rosa Maria Rodrigues Pereira; Berilo Langer; Jayme Diament; Ricardo Manoel de Oliveira; Wilson Cossermelli

From the Laboratory of Investigation in Experimental Therapeutics and Laboratory of Investigation in Rheumatology, University of São Paulo, School of Medicine, São Paulo, BRASIL

Address for correspondence Address for correspondence: Dra. Consuelo Junqueira Rodrigues Faculdade de Medicina da Universidade de São Paulo, Laboratório de Reumatologia Av. Dr. Arnaldo, 455 CEP 01246 São Paulo, SP, Brasil

SUMMARY

The authors report three patients with subcutaneous erythematous nodules in different phases of development, inespecific systemic symptoms, positive PPD test, and normal chest X-rays. The histopathological study of the older nodules showed a granulomatous arteritis with a few acid-fast bacilli in the vascular wall. The nodules at an early phase showed an inespecific panniculitis with some acid-fast bacilli in apparently normal cutaneous vessels. These findings suggest that the mycobacterium has a vascular tropism and may cause a primary granulomatous arteritis.

Key words: Erythema induratum Bazin; Erythema nodosum; Vasculitis.

RESUMO

Os autores descrevem três casos de pacientes com nódulos subcutâneos em diferentes fases de evolução, com sintomas sistêmicos inespe-cíficos, PPD positivo e raio-X de tórax normal. O estudo anátomo-patológico dos nódulos antigos mostrou arterite granulomatosa e com raros bacilos álcool-ácido resistentes na parede vascular; os nódulos recentes mostraram paniculite inespecífica com alguns bacilos álcool-ácido resistentes na parede de vasos cutâneos aparentemente normais. Esses achados sugerem que a micobactéria tem um tropismo vascular e pode causar arterite granulomatosa.

Full text available only in PDF format.

Texto completo disponível apenas em PDF.

ACKNOWLEDGEMENTS

Maria de Fátima de Almeida and Noemi Nosomi Taniwaki are acknowledged for technical assistance and Yukie Umeki for typing this manuscript.

Recebido para publicação em 16/2/1990.

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  • Address for correspondence:

    Dra. Consuelo Junqueira Rodrigues
    Faculdade de Medicina da Universidade de São Paulo, Laboratório de Reumatologia
    Av. Dr. Arnaldo, 455
    CEP 01246 São Paulo, SP, Brasil
  • Publication Dates

    • Publication in this collection
      12 Sept 2006
    • Date of issue
      Oct 1990

    History

    • Received
      16 Feb 1990
    Instituto de Medicina Tropical de São Paulo Av. Dr. Enéas de Carvalho Aguiar, 470, 05403-000 - São Paulo - SP - Brazil, Tel. +55 11 3061-7005 - São Paulo - SP - Brazil
    E-mail: revimtsp@usp.br