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Theoretical and experimental study of the Bioactivity Testing Solution (BTS)

The contact of materials such as metals used as biomaterials in simulated body solutions (SBF) that mimetize the inorganic and acellular part of blood plasma allows the evaluation of its capacity of calcium phosphate precipitation. These phosphates can precipitate by biomimetic route in the interface material-tissue, being important when the material is in vivo implanted. In addition, there are several solutions that favor this biomimetic deposition such as named as Kokubo, Neuman and Ringer, and they are used in the promotion of precipitation. These solutions employed several reagents; some of them are not necessary in the stoichiometry of the main calcium phosphates. From a theoretical study that showed the possibility of using a simplified solution, we decide to investigate this solution in vitro precipitation conditions. In this way, samples of Ti were grinding, treated with 1M NaOH and subsequently exposed to simplified SBF. After the exposure of surfaces, they were analyzed by SEM/EDS and XRD to characterize the deposits. The experimental results show that the precipitated phase is octacalcium phosphate, which corroborate theoretical findings.

Titanium; bioactivity; SBE


Laboratório de Hidrogênio, Coppe - Universidade Federal do Rio de Janeiro, em cooperação com a Associação Brasileira do Hidrogênio, ABH2 Av. Moniz Aragão, 207, 21941-594, Rio de Janeiro, RJ, Brasil, Tel: +55 (21) 3938-8791 - Rio de Janeiro - RJ - Brazil
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