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Radiodosimetric evaluation through MCNP-5 code of the radiosteoplasty on bone tumors in members

The present paper addresses the computational dosimetry of a clinical case involving a child with tumor on the fibula, whose tomographic images were digitalized and manipulated by the SISCODES program, in order to generate a 3D voxel model, representative of the clinical case. Later, it was plugged in to the Monte Carlo MCNP-5 code and the model was used for absorbed dose prediction. Nuclear features of the cement incorporating the radionuclide composite were presented with its respectively specific activity. The spatial dose rate distribution from the gamma emission of the Sm-153 was 9.02 10-5 GyhMBq-1 and the imparted absorbed dose was 6.23 10-3 GyhMBq-1. Therefore, 7400 MBq produced a tumor dose of 47 Gy, suitable for the local tumor control. As conclusion, an adequate spatial dose distribution supports the application of this protocol, namely radiosteoplasty, as a therapy for bone tumors on the superior and inferior members. The radiosteoplasty is a technique that is in development in the research group NRI- Núcleo de Radiações Ionizantes at UFMG. It is a procedure that consists of the injection of a radioactive biomaterial into the bone structure affected by cancer, following pain reduction, structural resistance increasing, and mainly tumor or metastasis control in situ.

Computational dosimetry; radiosteoplasty; bone tumors; MCNP


Laboratório de Hidrogênio, Coppe - Universidade Federal do Rio de Janeiro, em cooperação com a Associação Brasileira do Hidrogênio, ABH2 Av. Moniz Aragão, 207, 21941-594, Rio de Janeiro, RJ, Brasil, Tel: +55 (21) 3938-8791 - Rio de Janeiro - RJ - Brazil
E-mail: revmateria@gmail.com