Zapata-Sudo, et al. [11 Wewege MA, Thom JM, Rye KA, Parmenter BJ. Aerobic, resistance or combined training: A systematic review and meta-analysis of exercise to reduce cardiovascular risk in adults with metabolic syndrome. Atherosclerosis. 2018;274:162-71.] |
18 Wistar rats Control group n=6 Myocardial Infarction group=12 n=6 with açai supplementation, n=6 without açai supplementation |
100 mg/kg/day açai seed extract, for 4 weeks. |
Treadmill run until fatigue (8m/min, 12m/min, 18m/min with 3 min each step) |
Performance total running distance Hemodynamic parameters SAP, DAP, left ventricular systolic pressure, left ventricular diastolic pressure, relaxation rate, cardiac hypertrophy Other rat weight, collagen volume of the left ventricle |
Performance ↓exercise intolerance Hemodynamic parameters ↑SAP, ↑Left ventricular systolic pressure, ↓Left ventricular diastolic pressure, ↓cardiac hypertrophy Other ↓ Collagen Volume Fraction |
de Bem, et al. [22 Rezende LFM, Sá TH, Markozannes G, Rey-López JP, Lee IM, Tsilidis KK, et al. Physical activity and cancer: an umbrella review of the literature including 22 major anatomical sites and 770 000 cancer cases. Br J Sports Med. 2018;52(13):826-33.] |
40 diabetic rats n=10 rats (açai+exercise) n=10 rats (exercise) n=10 rats (açai+sedentary) n=10 rats (sedentary) 40 Control rats n=10 rats (açai+exercise) n=10 rats (exercise) n=10 rats (açai+sedentary) n=10 rats (sedentary) |
200 mg /kg/day of acai seed extract for 4 weeks |
Treadmill running (30 min/day; 5 day/week, during 4 weeks at 50 to 60% of the maximal velocity) |
Serum assays TC, HDL, LDL, VLDL, TG, AST, ALT Western blotting LKB1, PLKB1, AMPK, pAMPK, SREBP-1C, ACC, pACC, MTP, ABCG5, ABCG8, HMGCo-A Others SOD, CAT, GPx, glycogen, liver weight, steatosis, carbonyl(plasma), carbony (liver), MDA(plasma), MDA(liver), 8-Isoprostane |
Western Blotting ↓GL final, ↓MTP, ↓HMGCoA-R, ↑ABCG8, Other ↓liver weight, ↓steatosis, ↓carbonyl (plasma) ↓MDA (plasma), ↓% 8-isoprostane, ↑SOD (liver), ↑GPx (liver) |
de Bem, et al. [33 Pan Q, Li Q, Deng W, Zhao D, Qi L, Huang W, et al. Prevalence of and Risk Factors for Peripheral neuropathy in chinese patients with diabetes: a multicenter cross-sectional study. Front Endocrinol (Lausanne). 2018;9:617.] |
40 diabetic rats n=10 rats (açai+exercise) n=10 rats (exercise) n=10 rats (açai+sedentary) n=10 rats (sedentary) 40 Control rats n=10 rats (açai+exercise) n=10 rats (exercise) n=10 rats (açai+sedentary) n=10 rats (sedentary) |
GA: 200mg / kg / day açai seed extract. For 4 weeks. GC: nothing |
Treadmill running (30 min /day; 5 day/week, during 4 weeks at 50 to 60% of the maximal velocity) |
Lipid profile TC, VLDL, HDL, LDL, TG, HbA1c Western Blotting IR, AKT, pAKT, GLUT-4, pAMPK Serum Assays IL-6, TNFα, GLP-1, Leptin Other Insulin, HOMA-IR, HOMA-B |
Diabetic group ↓HbA1C, ↓Insulin, ↓Homa-IR, ↓IR, ↑pAKT, ↑Adiponectin |
Soares, et al. [44 Powers SK, Jackson MJ. Exercise-induced oxidative stress: cellular mechanisms and impact on muscle force production. Physiol Rev. 2008;88(4):1243-76.] |
81 Wistar rats n=17 sedentary n=14 sedentary + chronic ASE n=18 training n=17 training + chronic ASE n=15 training + acute ASE |
200mg/kg/day for 5 weeks Training+ASE acute=30 min before test |
Treadmill running until fatigue (3m/min, increasing 4m/min every 3 min until exhaustion) |
Performance total running distance time Western blotting p-eNOS, MDA, SOD, GPX, Catalase, NO2, PAMPK/AMPK, SIRT-1, Nrf-2, PGC1α Other Weight, glucose, lactate. |
Performance total running distance: ↑training+chronic ASE time: ↑training+chronic ASE Western blotting Training+acute ASE ↑p-eNOS, ↑MDA Training+chronic ASE ↑SOD, ↑GPX, ↑Catalase, ↑NO2, ↑P-AMPK/AMPK, ↑SIRT-1, ↑Nrf-2, ↑PGC1α |
Lavorato, et al. [55 Powers SK, Nelson WB, Hudson MB. Exercise-induced oxidative stress in humans: cause and consequences. Free Radic Biol Med. 2011;51(5):942-50.] |
50 rats n=10 rats (Control) n=10 rats (High-fat Diet) n=10 rats (High-fat Diet + Açai) n=10 rats (High-fat Diet + AET) n=10 rats (High-fat Diet + Açai + AET) |
GA: 100mg/kg/day açai seed extract, for 4 weeks. GC: nothing |
Treadmill running until fatigue (5 times/week, 60 min/day, 60-70% of maximum running speed (MRS), for 8 weeks) |
Performance total running distance time Body composition and running capacity IBM, FBM, BMG, BW, HW, VW, LVW, Initial TTF, Final TTF Western blotting mRNA, MDA, CP, SOD, Catalase, GTS. |
Performance total running distance: ↑TTF+HAT Body composition and running capacity ↑BGM ↑FinalTTF Western blotting Training+chronic ASE ↓MDA, ↓CP, ↑Catalase, ↑GTS |