Breastfeeding and the anthropometric profile of children with sickle cell anemia receiving follow-up in a newborn screening reference service

Zeni Drubi Nogueira Ney Boa-Sorte Maria Efigênia de Queiroz Leite Márcia Miyuki Kiya Tatiana Amorim Silvana Fahel da Fonseca About the authors

OBJECTIVE:

To study the breastfeeding history (BF) and the anthropometric status of children with Sickle Cell Disease (SCD).

METHODS:

A cross-sectional study of 357 children with SCD aged between 2 and 6 years, regularly followed at a Newborn Screening Reference Service (NSRS) between November 2007 and January 2009. The outcome was anthropometric status and the exposures were: BF pattern, type of hemoglobinopathy and child's age and gender.

RESULTS:

The mean (SD) age was 3.7 (1.1) years, 52.9% were boys and 53.5% had SCA (hemoglobin SS). The prevalence of exclusive breastfeeding (EBR) up to six months of age was 31.5%, the median EBR times (p25-p75) was 90.0 (24.0-180.0) days and the median weaning ages (p25-p75) was 360.0 (90.0-720.0) days respectively. Normal W/H children experienced EBR for a mean duration almost four times longer than malnourished children (p=0.01), and were weaned later (p<0.05). Height deficit was found in 5.0% of children, while all the children with severe short stature had had SCA (hemoglobin SS) and were older than 4 years of age.

CONCLUSIONS:

EBF time and weaning age were greater than that found in the literature, which is a possible effect of the multidisciplinary follow-up. Duration of EBF and later weaning were associated with improved anthropometric indicators.

Breast-feeding; Nutritional status; Sickle cell anemia; Hemoglobin SC disease; Neonatal screening


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