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Short Communication • Rev. Soc. Bras. Med. Trop. 52 • 2019 • https://doi.org/10.1590/0037-8682-0156-2019   copy

Brazilian Spotted Fever Prevention through a Nonlethal Capybara Population Control Strategy

Authorship SCIMAGO INSTITUTIONS RANKINGS

Abstract

INTRODUCTION:

Brazilian spotted fever (BSF), a lethal tick-borne Rickettsioses (2000 - 2018 >600 human deaths) involving synanthropic capybara as host.

METHODS:

We introduced an alternative to mitigate human-capybara conflicts and epidemiologic concerns of BSF. Complex aspects like transmission dynamics, risk areas, host mobility, and birth rate control, were considered to develop a prevention strategy using an anti-GnRH vaccine.

RESULTS:

The propositioned immunocontraceptive potentially remove and prevent the spread of BSF from endemic areas.

CONCLUSIONS:

We propose the anti-GnRH vaccine as a BSF prevention strategy based on these favorable results.

Keywords:
Immunocontraception; Anti-GnRH; GonaCon; Hydrochoerus hydrochaeris; Rickettsia; Amblyomma sculptum

Sociedade Brasileira de Medicina Tropical - SBMT Caixa Postal 118, 38001-970 Uberaba MG Brazil, Tel.: +55 34 3318-5255 / +55 34 3318-5636/ +55 34 3318-5287, http://rsbmt.org.br/ - Uberaba - MG - Brazil
E-mail: rsbmt@uftm.edu.br
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