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Frequency of anti- Toxoplasma gondii IgA, IgM, and IgG antibodies in high-risk pregnancies, in Brazil

Abstract:

INTRODUCTION

Toxoplasmosis during pregnancy can be severe; thus, it is essential to diagnose the disease via serological tests.

METHODS

An enzyme-linked immunosorbent assay (ELISA) was used to investigate anti-Toxoplasma gondii immunoglobulin A (IgA), M (IgM) and G (IgG) antibodies in 62 high-risk pregnant women.

RESULTS

Forty-three (69.4%) women were positive for IgA, 31 (50%) for IgG, and 57 (91.9%) for IgM; 4 (6,5%) were positive for IgA but negative for IgM; 10 (16.1%) were negative for IgA and IgM but positive for IgG.

CONCLUSIONS

Testing for these antibodies can help diagnose infection in pregnant women, thereby contributing to clinical management.

Keywords:
Toxoplasma gondii; Acute infection; High-risk pregnancy

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