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First report of the aac(6’)-Ib-cr gene in Providencia stuartii isolates in Brazil

Abstract

INTRODUCTION:

The aac(6’)-Ib-cr and bla KPC genes are spreading among Enterobacteriaceae species, including Providencia stuartii, in some countries of world.

METHODS:

These genes were investigated in 28 P. stuartii isolates from a public hospital in Recife, Pernambuco, Brazil, by PCR and sequencing.

RESULTS:

The aac(6’)-Ib-cr gene was detected in 16 resistant isolates, and the bla KPC gene was seen in 14.

CONCLUSIONS:

The presence of these genes in P. stuartii multi- and extensively drug-resistant isolates indicates that the resistance arsenal of this species is increasing, thus limiting the therapeutic options.

Keywords:
Antimicrobial agents; Enterobacteriaceae; MDR genes; Providencia stuartii

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