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Short Communication • Rev. Soc. Bras. Med. Trop. 49 (02) • Mar-Apr 2016 • https://doi.org/10.1590/0037-8682-0275-2015   copy

Factors associated with non-adherence to the treatment of vivax malaria in a rural community from the Brazilian Amazon Basin

Authorship SCIMAGO INSTITUTIONS RANKINGS

Abstract:

INTRODUCTION

We investigated the association between demographic and behavioral factors and non-adherence to antimalarial therapy.

METHODS

A demographic questionnaire and 5-item self-reported questionnaire regarding non-adherence were completed by 135 patients after treatment for Plasmodium vivax.

RESULTS

Treatment interruption, but not demographic factors, was significantly associated with non-adherence to therapy. The likelihood of non-adherence was 5.16 times higher when the patients felt better than when they felt worse. The relative risk of parasitic resurgence was 3.04 times higher in non-adherent patients.

CONCLUSIONS

Treatment interruption is significantly associated with treatment adherence.

Keywords:
Malaria; Resurgence; Adherence

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