We have treated 120 patients between 17 and 19 years old with intestinal or hepatointestinal forms of Schistosoma mansoni infection. Patients were matched in pairs according to the number of eggs per gram of faeces. One member was given oxamniquine in a single dose of 15 mg/kilo/ body weight, and the other praziquantel in a dose of 55mg/kilo/ of body weight, both in capsule form. Of the 106 patients adequately evaluated (at least two stool examinations after treatment) 44 (83%) praziquantel group and 41 (77,3%) of the oxamniquine group had no eggs in the faeces. Both drugs were well tolerated but oxamniquine appeared slightly better in this regard.
Schistosomiasis mansoni; Treatment; Oxamniquine; Praziquantel