Cholinesterase activity was measured in the plasma and erythrocytes from 32 individuals. The 16patients, in whon the diagnosis of Chagasic megacolon confirmed, hada significantly lower concentration of the enzyme both in plasma (1.540 ± 318 Yl/L) and erythrocytes (53.2 ± 9.1 Ul/g Hb) when compared with the 16 Controls in whom, the plasma and erythrocyte cholinesterase leveis were, respectively, 2.554 ± 823and 63.6 ± 11 Ul/g Hb. The results show a correlation between the systemic cholinesterase activity and the histopathological findings.
Acetylcholinesterase; Pseudocholinesterase; Megacolon; Chagas' Disease