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Exposure to Leishmania spp. infection and Lutzomyia spp. in individuals living in an area endemic for visceral leishmaniasis in Brazil

Abstract

INTRODUCTION:

This study aimed to investigate human exposure to Leishmania spp. infection and sandflies in an area endemic for the disease.

METHODS:

The presence of antibodies specific for Leishmania spp. and saliva of Lutzomyia spp. and that of L. infantum DNA in blood were evaluated.

RESULTS:

Antibodies against Leishmania spp. and sandfly saliva were observed in 20.8% and 37.7% of individuals, respectively. DNA of Leishmania spp. was amplified from the blood of one patient.

CONCLUSIONS:

The results suggest that Leishmania spp. infection may be underdiagnosed in this area.

Keywords:
Antibodies; Humoral immunity; Sandfly saliva; Serology

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