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Short Communication • Rev. Soc. Bras. Med. Trop. 49 (03) • May-Jun 2016 • https://doi.org/10.1590/0037-8682-0360-2015   copy

Canine antibody response to Lutzomyia longipalpis saliva in endemic area of visceral leishmaniasis.

Authorship SCIMAGO INSTITUTIONS RANKINGS

Abstract:

INTRODUCTION:

Canine exposure to Lutzomyia longipalpis bites and the potential of Leishmania infantum transmissibility for the vector were evaluated.

METHODS

Immunoglobulin G (IgG) anti-Lu longipalpis saliva and -L. infantum, and blood parasite load were determined in dogs from endemic areas of visceral leishmaniasis.

RESULTS

Blood parasitism was similar between symptomatic and asymptomatic dogs. IgG anti-L. infantum was higher in symptomatic dogs, but IgG anti-Lu. longipalpis saliva was mostly observed in higher titers in asymptomatic dogs, indicating vector preference for feeding on asymptomatic dogs.

CONCLUSIONS

Our data suggest a pivotal role of asymptomatic dogs in L. infantum transmission in endemic areas.

Keywords:
Canine leishmaniasis; Anti-Lutzomyia longipalpis saliva antibody; Transmissibility

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