Abstract
INTRODUCTION:
Human herpesvirus (HHV)-7 establishes a latent infection during the lifetime of the host and can reactivate after the primary infection, leading to lytic replication in immunosuppressed patients.
METHODS:
This study aimed to develop an enzyme-linked immunosorbent assay (ELISA) to identify HHV-7 serum antibodies and compare its performance with that of an indirect immunofluorescence assay (IFA).
RESULTS:
Serum samples (n=102) were tested by IgG-IFA and by ELISA. IFA and ELISA showed IgG-positive results in 77 and 73 samples, respectively. Qualitative concordance of 96% was demonstrated between the two techniques.
CONCLUSIONS:
ELISA may be useful to diagnose HHV-7 infection.
Keywords:
ELISA; IFA; HHV-7; Serological Assay
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