Ethical control of researches whose results offer high risk to the health of the population

Veloso, Sandra Ceciliano de Souza; Cunha, Thiago Rocha da; Garrafa, Volnei

doi:10.1590/0103-1104201611018

Acessibilidade / Reportar erro

Brasil

Español English

sumário « anterior atual seguinte »

Sumário

REVIEW • Saúde debate 40 (110) • Jul-Sep 2016 • https://doi.org/10.1590/0103-1104201611018 copy

Ethical control of researches whose results offer high risk to the health of the population

Authorship SCIMAGO INSTITUTIONS RANKINGS

ABSTRACT

This article discusses the emergence of ethical conflicts between the need to ensure the advances in science and the need to control their possible consequences for humanity. A research was carried out to analyze the scientific Latin-American literature and the Brazilian legal and regulatory bases on the ethical regulation of researches that do not involve humans as subjects of the intervention, and found the absence of norms for the regulation of such researches and the lack of scientific literature on the subject. Considering the severity of the impact that certain researches may cause to the health of the population, the conclusion is that there is the need to establish strong measures for their ethical control.

KEYWORDS
Ethics in research; Bioethical issues; Codes of ethics

Title	Approaches and Considerations
1. Tecnologia, aids e ética em pesquisa (SCHEFFER, 2000SCHEFFER, M. Tecnologia, Aids e ética em pesquisa. Interface (Botucatu), Botucatu, v. 4, n. 6, p. 173-176, 2000.).	Discussion on ethics in research with human beings, using the example of multicenter studies of antiretroviral therapy for Hiv in developing countries.
2. Pensamientos de Juan de Dios Vial Correa en torno a: los problemas éticos en ciencia e investigación (CORREA, 2004CORREA, J. D. V. Pensamientos de Juan de Dios Vial Correa en torno a: los problemas éticos en ciencia e investigación. ARS Médica, Santiago, v. 9, p. 30-129, 2004.).	Special edition of journal comprising articles on issues such as: ethics of Medical act, human embryo statute, human genome and cloning.
3. A responsabilidade do pesquisador ou sobre o que dizemos acerca da ética em pesquisa (*PADILHA et al., 2005*PADILHA, M. I. C. S. et al. A responsabilidade do pesquisador ou sobre o que dizemos acerca da ética em pesquisa. Texto & Contexto - Enfermagem, Florianópolis, v. 14, n. 1, p. 96-105, 2005.).	Ethics in Nursing. Refers to the use of scientific research for destructive purposes. But the main approach is on studies involving human beings.
4. A ética na pesquisa e a epistemologia do pesquisador (RIOS, 2006RIOS, T. A. A ética na pesquisa e a epistemologia do pesquisador. Psicologia em Revista, Belo Horizonte, v. 12, n. 19, p. 80-86, 2006.).	Broad discussion on ethics in sciences in general, not focusing on or describing any kind of research.
5. A produção científica e a ética em pesquisa (MIRANDA, 2006MIRANDA, L. C. D. A produção científica e a ética em pesquisa. Revista do Colégio Brasileiro de Cirurgiões, Rio de Janeiro, v. 33, n. 6, p. 411-412, 2006.).	Discusses the Free and informed Consent Form in the protocols of research involving human beings and the qualification of the research ethics Centers.
6. Reflexiones éticas sobre la investigación científica en Biomedicina desde el prisma de la Universidad Médica (CANO, 2006CANO, M. C. A. Reflexiones éticas sobre la investigación científica en Biomedicina desde el prisma de la Universidad Médica. Revista Cubana de Investigaciones Biomedica, Ciudad de La Habana, v. 25, n. 1, 2006.).	Addresses ethical reflections on all types of research. But the focus is on researches involving human beings.
7. Conocimientos de la ética de la investigación científica (*HERNÁNDEZ et al.,* 2008**HERNÁNDEZ, I. A. et al. Conocimientos de la ética de la investigación científica. Revista Cubana de Medicina General Integral, Ciudad de La Habana, v. 24, n. 3, 2008.).	Reports a study conducted at the Faculty of Medical sciences of Havana to access the knowledge of professionals on ethics in research involving human beings.
8. Ética e pesquisa (NOSELLA, 2008NOSELLA, P. Ética e pesquisa. Educação & Sociedade, Campinas, v. 29, n. 102, p. 255-273, 2008.).	Extensively addresses research ethics, in all fields of knowledge, with historical philosophical fundaments of the relation between research activities and moral obligations, throughout history.
9. Ética e Investigación Científica en la sociedad Globalizada (NORERO; TORO; CONTERERAS, 2009NORERO, C. V.; TORO, C. A.; CONTERERAS, J. P. Ética e Investigación Científica en la Sociedad Globalizada. Revista Chilena de Pediatría, Santiago, v. 80, n. 4, p. 305-307, 2009.).	Discusses ethical control in scientific research broadly. Concludes on the importance of ethics in professional societies and the need to develop an ‘ethics for the future’ concerned about the new generations and their sustainability.
10. Aspectos Éticos y legales de la investigación Científica en Brasil (SILVA; BARRERA GARCÍA; SILVA, 2010SILVA, P. R.; BARRERA-GARCÍA, R. C.; SILVA, R. Aspectos Éticos y Legales de La Investigación Científica en Brasil. Acta Bioethica, Santiago, v. 16, n. 1, p. 61-69, 2010.).	Survey on the ethical regulatory process of scientific research in Brazil. in the article there is no mention to researches whose results have impact on the health of the population.
11. Las investigaciones biotecnológicas. implicaciones éticas y sociales (DIAGO et al ., 2010DIAGO, N. B. et al. Las investigaciones biotecnológicas. Implicaciones éticas y sociales. Mediciego, Ciego de Ávila, v. 16, supl. 2, dic. 2010.).	Analyses the social impact of biotechnology applied in humans, focusing on genetics therapy and the human genome project.
12. O papel da plausibilidade na avaliação da pesquisa científica (ALMEIDA, 2011ALMEIDA, R. M. V. R. O papel da plausibilidade na avaliação da pesquisa científica. Revista Saúde Pública, São Paulo, v. 45, n. 3, p. 617-620, 2011.).	Addresses methodological issues, such as: Hypothesis test. reproducibility of tests. statistical methods and procedures.
13. Retos de la bioética frente a la biotecnología. necesidad de la educación en bioética (RESTREPO, 2011RESTREPO, P. A. Retos de la bioética frente a la biotecnología. Necesidad de la educación en bioética, NOVA Publicación Científica, Bogotá, v. 9 n. 15, 2011.).	Addresses bioethics education, pointing to the need of bioethics education with anthropological premises that respect the human being.
14. Ética em pesquisa: antigos conhecidos, novos desafios (COSTA, 2013COSTA, A. S. Ética em Pesquisa: antigos conhecidos, novos desafios. Cadernos Saúde Coletiva, Rio de Janeiro, v. 21, n. 3, p. 235-236, 2013.).	States that in the Research Ethics Committees for researches involving human beings, research ethics should not be seen as bureaucracy to fulfill certain criteria or fill-in official forms, but as an utmost necessary agenda, completing in a crucial way the vast framework of functions that embrace the principle of respect for the integrity of all beings.
15. Interconexão entre Direito e bioética à luz das dimensões teórica, institucional e normativa (CARREIRO; OLIVEIRA, 2013CARREIRO, N. M. S.; OLIVEIRA, A. A. S. Interconexão entre Direito e bioética à luz das dimensões teórica, institucional e normativa. Revista Bioética, Brasília, DF, v. 21, n. 1, p. 53-61, 2013.).	Verifies that bioethics may help the Judicial Branch and the law enforcer to make compatible judicial rationality and ethical reflection provided by new scientific paradigms. Cites in the introduction the techno-scientific advances and issues resulting from the unsafety generated by the human destructive capacity, but broadly and not specifying the research results.
16. Normas de bioética para una investigación científica (*AMATRIAIN et al* ., 2013**AMATRIAIN, R. M. C. et al. Normas de bioética para una investigación científica/Bioethical standards for scientific research. Revista de la Asociación Médica Argentina, Buenos Aires, v. 126, n. 3, p. 38-45, 2013.).	Discusses the compliance with bioethical regulations in studies involving human beings, focusing on the use of “Double Standard’.
17. Una mirada filosófica a la ética de la Investigación (LABOY, 2013LABOY, R. G. Una mirada filosófica a la ética de la investigación. Revista Bioética, Brasília, DF, v. 21, n. 1, p. 43-52, 2013.).	Questions the frauds in researches and the ethical conduct in researches involving human beings. Considers that the codes of ethics in researches have been inefficient for many scientists. Concludes for the need of a philosophical reflection of ethics and moral in research.
18. Quality perception in research laboratories from FIOCRUZ after QMS implementation (*PRESOT et al* ., 2014)**PRESOT, I. M. et al. Quality perception in research laboratories from Fiocruz after QMS implementation. Revista Administração Pública, Rio de Janeiro, v. 48, n. 1, p. 237-252, 2014..	Describes the perception of collaborators after the implementation of the Quality system in a research laboratory. As a result, biosafety, training and ethics were considered the most important parameters.

Centro Brasileiro de Estudos de Saúde Av. Brasil, 4036, sala 802, 21040-361 Rio de Janeiro - RJ Brasil, Tel. 55 21-3882-9140, Fax.55 21-2260-3782 - Rio de Janeiro - RJ - Brazil
E-mail: revista@saudeemdebate.org.br

Acompanhe os números deste periódico no seu leitor de RSS

[1] Conflict of interests: non-existent