The Hematology, Transfusion and Cell Therapy Journal is a three-monthly scientific publication of the Associação Brasileira de Hematologia, Hemoterapia e Terapia Celular (ABHH), the Sociedade Brasileira de Transplante de Medula Óssea (SBTMO), the Associazione Italo-Brasiliana di Ematologia (AIBE), and the Sociedade Brasileira de Oncologia Pediátrica (SOBOPE). Subject areas suitable for publication include, but are not limited to the following fields:

• Anemia
• Bone marrow transplantation
• Coagulation disorders
• Genetics
• Neoplastic diseases
• Pediatric Hematology
• Stem cell therapy
• Transfusion medicine

• LILACS
• EXTRAMED
• Scopus
• Pubmed/PMC
• Capes/Qualis

All content of the journal, except where identified, is licensed under a Creative Commons attribution-type BY-NC-ND.

The journal is sponsored by:

• The Associação Brasileira de Hematologia, Hemoterapia e Terapia Celular (ABHH)
  

Editor in Chief

• Fernando Ferreira Costa – Faculdade de Ciências Médicas da Universidade Estadual de Campinas (Unicamp), Campinas, SP, Brazil

Deputy Editor

• Eduardo Magalhães Rego – Faculdade de Medicina da Universidade de São Paulo, (USP), Ribeirão Preto, SP, Brazil

• Alfredo Mendrone Júnior – Fundação Pró-Sangue - Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (HCFMUSP), São Paulo, SP, Brazil, alfredo.mendrone@prosangue.sp.gov.br
• Behnaz Bayat - Justus-Liebig University Giessen – Germany, Behnaz.Bayat@immunologie.med.uni-giessen.de
• Belinda Pinto Simões -  Instituto Gonçalo Moniz (IGM) da Fiocruz-Salvador, BA, Brazil, bpsimoes@fmrp.usp.br
• Carlos Sérgio Chiattone – Faculdade de Ciências Médicas da Santa Casa de São Paulo (FCMSCSP), São Paulo, SP, Brazil, carlos.chiattone@terra.com.br
• Cármino Antonio de Souza – Faculdade de Ciências Médicas da Universidade Estadual de Campinas (Unicamp), Campinas, SP, Brazil, carmino@ynicamp.br
• Dante Mário Langhi Junior – Faculdade de Ciências Médicas da Santa Casa de São Paulo (FCMSCSP), São Paulo, SP, Brazil, hemoterapia@santacasasp.org.br
• Dimas Tadeu Covas – Faculdade de Medicina da Universidade de São Paulo (USP), Ribeirão Preto, SP, Brazil, dcovas@me.com
• Elvira Deolinda Rodrigues Pereira Velloso - Universidade de São Paulo, Faculdade de Medicina da Universidade de São Paulo (FMUSP) , São Paulo, SP, Brazil, elvira.velloso@yahoo.com.br
• Fabíola Traina -Universidade de São Paulo Faculdade de Medicina de Ribeirão Preto (FMRP USP), Ribeirão Preto, SP, Brazil, ftraina@fmrp.usp.br
• Helio Moraes Souza, Universidade Federal do Triângulo Mineiro (UFTM), Uberaba, MG, Brazil, helio.moraes@uftm.edu.br
• Irene Lorand-Metze – Faculdade de Ciências Médicas da Universidade Estadual de Campinas (Unicamp), Campinas, SP, Brazil, ilmetze@gmail.com
• José Orlando Bordin – Escola Paulista de Medicina -Universidade Federal de São Paulo (Unifesp) São Paulo, SP, Brazil, jobordin@gmail.com
• Luis Fernando S. Bouzas – Instituto Nacional do Câncer (INCA), Rio de Janeiro, RJ, Brazil, luisbouzas@terra.com.br
• Marcelo Pasquini – Medical College of Wisconsin, Wisconsin, USA, mpasquini@mcw.edu
• Márcio Nucci – Faculdade de Medicina da Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro, RJ, Brazil, mnucci@hucff.ufrj.br
• Marcos Borato Viana – Faculdade de Medicina da Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG, Brazil, vianamb@gmail.com
• Marcos de Lima – University Hospitals Case Medical Center, Cleveland, USA, Marcos.deLima@UHhospitals.org
• Margareth Castro Ozello – Faculdade de Ciências Médicas da Universidade Estadual de Campinas (Unicamp), Campinas, SP, Brazil, margarethozelo@gmail.com
• Maria Helena Pitombeira – Faculdade de Medicina da Universidade Federal do Ceará (UFC), Fortaleza, Brazil, mspit@terra.com.br
• Maria Stella Figueiredo, Universidade Federal de São Paulo (Unifesp), São Paulo, SP, Brazil, stella.figueiredo@unifesp.br
• Marilda de Souza Gonçalves - Instituto Gonçalo Moniz (IGM) da Fiocruz-BA, Salvador, BA, Brazil
• Nelson Hamerschlak – Hospital Israelita Albert Einstein, São Paulo, SP, Brazil, hamer@einstein.br
• Nelson Spector – Faculdade de Medicina da Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro, RJ, Brazil, nelson.spector@gmail.com
• Nicola Conran – Faculdade de Ciências Médicas da Universidade Estadual de Campinas (Unicamp), Campinas, SP, Brazil, nicconran@gmail.com
• Paulo Sérgio da Silva Santos - Faculdade de Odontologia de Bauru, Universidade de São Paulo (FOB USP), Bauru, SP, Brazil, paulosergiosilvasantos@gmail
• Roberto Passetto Falcão - Faculdade Medicina Ribeirão Preto, Universidade de São Paulo, São Paulo, SP, Brazil - rpfalcao@fmrp.usp.br
• Rodrigo Tocantins Calado – Faculdade de Medicina da Universidade de São Paulo, (USP), Ribeirão Preto, SP, Brazil, rtcalado@fmrp.usp.br
• Sara Teresinha Olalla Saad - Universidade Estadual de Campinas, Faculdade de Ciências Médicas da UNICAMP, Campinas, SP, Brazil, sara@unicamp.br
• Silvia Maria Meira Magalhães - Universidade Federal do Ceará, Hospital Universitário Walter Cantídio, Fortaleza, CE, Brazil, silviamm@ufc.br
• Suely Meireles Rezende - Universidade Federal de Minas Gerais, Faculdade de Medicina (FM UFMG), Belo Horizonte, MG, Brazil, srezende@medicina.ufmg.br
• Valder Arruda – The Children’s Hospital of Philadelphia, Philadelphia, USA, ARRUDA@email.chop.edu
• Vanderson Rocha – Churchill Hospital, Oxford University Hospital, Oxford, UK, rocha.vanderson@hotmail.fr
• Vania Tietsche de Moraes Hungria, Faculdade de Ciências Médicas da Santa Casa de São Paulo (FCMSCSP), São Paulo, SP, Brazil, hungria@dialdata.com.br

• Alois Gratwöhl – University of Basel, Basel, Switzerland, Alois.gratwohl@unibas.ch
• Álvaro Urbano-Ispizua – University of Barcelona, Barcelona, Spain, aurbano@clinic.ub.es
• Andrea Bacigalupo – IRCCS San Martino, Genova, Italy, apbacigalupo@yahoo.com
• Ângelo Maiolino – Faculdade de Medicina da Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro, RJ, Brazil, angelomaiolino@gmail.com
• Antonio Fabron Júnior – Faculdade de Medicina de Marilia (FAMEMA), Marilia, SP, Brazil, angelomaiolino@gmail.com
• Christian Gisselbrecht – Hôpital Saint Louis Paris, Paris, France, christian.gisselbrecht@gmail.com
• Corrado Tarella – Università di Torino, Torino, Italy, corrado.tarella@unito.it
• Daniel Tabak – Centro de Tratamento Oncológico (Centron), São Paulo, SP, Brazil, dantabak@terra.com.br
• David Gòmez Almaguer – Universidad Autonoma de Nuevo Leon, Monterrey, NL, Mexico, dgomezalmaguer@gmail.com
• Elbio A. D’Amico – Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (HCFMUSP), São Paulo, SP, Brazil, elbio_damico@uol.com.br
• Enric Carreras – Hospital Clinic, Barcelona, Spain,  enric.carreras@fcarreras.es
• Frederico Luiz Dulley – Faculdade de Medicina da Universidade de São Paulo (USP), São Paulo, SP, Brazil, fldulley@usp.br
• Gino Santini – Ospedale San Martino, Genova, Italy, gino.santini@hsmartino.liguria.it
• Guillermo Dighiero – Institut Pasteur, Montevideo, Uruguay, dighiero@pasteur.fr
• Guillermo Ruiz-Arguelles – Universidad Popular Autónoma del Estado de Puebla, Mexico, Puebla, Mexico, gruiz1@clinicaruiz.com.
• Jesus Fernando San Miguel – Hospital Universitario de Salamanca, Salamanca, Spain, sanmigiz@usal.es
• João Carlos Pina Saraiva – Faculdade de Medicina da Universidade Federal do Pará (UFPA), Belém, Brazil, jocasa21@yahoo.com.br
• Laércio de Melo – Programa de Controle de Qualidade em Imuno Hematologia da Associação Brasiliera de Hematologia, Hemoterapia e Terapia Celular, rb.moc.aigolotamehonumi@oicreal
• Lílian Maria Castilho – Faculdade de Ciências Médicas da Universidade Estadual de Campinas (Unicamp), Campinas, SP, Brazil, castilho@unicamp.br
• Linamara Rizzo Battistella – Faculdade de Medicina da Universidade de São Paulo (USP), São Paulo, SP, Brazil, linamara@usp.br
• Lucia Mariano da Rocha Silla – Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brazil, lsilla@hcpa.edu.br
• Marcos Antonio Zago – Faculdade de Medicina da Universidade de São Paulo (USP), Ribeirão Preto, SP, Brazil, marazago@usp.br
• Maria de Lourdes L. F. Chauffaile – Escola Paulista de Medicina -Universidade Federal de São Paulo (UNIFESP), São Paulo, SP, Brazil, chauffaille@unifesp.br
• Maria do Socorro P. de Oliveira – Instituto Nacional de Câncer (INCA), Rio de Janeiro, RJ, Brazil, mpombo@inca.gov.br
• Mario Cazzola – Università di Pavia, Pavia, Italy, mario.cazzola@unipv.it
• Mary Evelyn Flowers – Fred Hutchinson Cancer Research Center, Seattle, USA, mflowers@fhcrc.org
• Nelson Abrahin Fraiji – Fundação Hospitalar de Hematologia e Hemoterapia do Amazonas (HEMOAM), Manaus, AM, Brazil, nfraiji@ig.com.br
• Nelson J. Chao – Duke University Medical Center, Durham, USA, chao0002@mc.duke.edu
• Paul M. Ness – Johns Hopkins University School of Medicine, Baltimore, USA, pness@jhmi.edu
• Paulo César Naoum – Academia de Ciência e Tecnologia, São José do Rio Preto, SP, Brazil, a.c.t@terra.com.br
• Pedro Enrique Dhorlliac-Llacer – Faculdade de Medicina da Universidade de São Paulo (USP), São Paulo, SP, Brazil, llacer.ops@terra.com.br
• Raul C. Ribeiro – St Jude Children's Research Hospital, Memphis, TN, USA, raul.ribeiro@stjude.org
• Raul Gabus – Institut Pasteur de Montevideo, Montevideo, Uruguay, gabusraul@gmail.comt
• Ricardo Pasquini – Faculdade de Medicina da Universidade Federal do Paraná (UFPR), Curitiba, PR, Brazil, r.pasquini@uol.com.br
• Richard K. Burt – Northwestern University Feinberg School of Medicine, Chicago, USA, rburt@northwestern.edu
• Sergio Giralt – Memorial Sloan Kettering Cancer Center, New York, NY, USA, giralts@mskcc.org
• Vânia Tietsche Hungria – Faculdade de Ciências Médicas da Santa Casa de São Paulo (FCMSCSP), São Paulo, SP, Brazil, hungria@dialdata.com.br
• Vicente Odone Filho – Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (HCFMUSP), São Paulo, SP, Brazil, odone@uol.com.br

The Hematology, Transfusion and Cell Therapy Journal (ISSN 2531-1379), the official scientific publication of the Associação Brasileira de Hematologia, Hemoterapia e Terapia Celular, Sociedade Brasileira de Transplante de Medula Óssea, Associazione Italo-Brasiliana di Ematologia and Sociedade Brasileira de Oncologia Pediátrica aims to promote scientific development in Hematology, Transfusion Medicine and related areas. All manuscripts, after initial acceptance by the editors, will be sent to at least two peer reviewers for analysis. Anonymity is guaranteed throughout the evaluation process. When considered necessary, a list of modifications will be sent to the authors to correct their work or justify their decision not to do so. The responsibility for opinions expressed in articles is solely of the authors.

Manuscripts should not be submitted simultaneously to more than one journal. This is an Open Access journal where articles are distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc-nd/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

General information

For any manuscript to be evaluated, it must be accompanied by the following documentation:

• Conflict of interest: Situations that may improperly influence the development or the conclusions of the work: participation in drug- or equipment-producing companies cited or used in the work, as well as competitors of these companies should be mentioned. Financial assistance, payments received for consultancies, relationships related to employment, etc. are also considered sources of conflict.
• Approval of the study by a Research Ethics Committee recognized by a National Research Ethics Committee such as CONEP;
• Articles that deal with clinical research involving human beings must include a statement in the Methods Section that all study participants signed an informed consent form. Authors should also confirm that the study was conducted in accordance with the Helsinki Declaration as revised in 2008;
• For works involving animal experimentation, the authors should confirm in the Methods Section that the study followed the rules contained in the Ethical Code for Animal Experimentation of the Council for International Organizations of Medical Sciences (CIOMS) [WHO Chronicle 1985; 39 (2): 51-6] and those produced in Brazil, the principles of the Brazilian College of Animal experimentation - COBEA (www.scielo.br/revistas/rbhh/www.cobea.org.br). Authors must complete the Declaration - Statement of Human and Animal Rights.

All randomized controlled trials and clinical trials submitted for publication must be registered in a clinical trials database. This is a guideline of the International Clinical Trial Registry Platform (ICTPR) of the World Health Organization (WHO) and the International Committee of Medical Journal Editors (ICMJE). The instructions for registration are available at http: www.scielo.br/revistas/rbhh/www.icmje.orgclintrialup.htm and registration can be attained in the Clinical Trials Database of the National Library of Medicine available at http://clinicaltrials.gov/ct/gui.

Technical requirements

1. Article identification: a) A concise however informative title; b) Complete names of authors without abbreviations and their institutions; c) Official name of the institution(s) to which the work should be attributed; d) Name, full address including telephone and e-mail of corresponding author; e) financial support (if any).

2. Abstract and keywords: Abstract in English without abbreviations of not more than 250 words. For Original Articles this should be structured with background, method, main results and conclusion. For the other article types, the abstract need not be structured but should contain information illustrating the importance of the work. Specify up to five keywords, which define the theme of the paper. The keywords should be based on MeSH (Medical Subject Headings) from the National Library of Medicine available at: http://decs.bvs.br. For clinical trials, indicate the International Clinical Trials Registry Number below the summary.

3. Manuscript content: a) Original Article: Used to publish the results of scientific research, it must be original and should comprise the following: Introduction, Objective, Method, Results, Discussion, Conclusion and References. The work should not exceed 4000 words (including references), up to 6 authors, up to 7 tables, illustrations and photos and up to 30 references; b) Special Article: With the same structure as original articles, Original Articles are reclassified by the Editor depending on their importance; C) Review Articles: narrative reviews addressing an important issue in the specialty. These articles should not exceed 5000 words (including references), a maximum of 7 tables, Figures and Photos and up to 60 references; d) Update in the Specialty: on a theme, method, treatment, etc. It must contain a brief history of the topic, its current state of knowledge and the reasons for the work; study methods (data sources, selection criteria), hypotheses, study lines, etc., criteria similar to review articles: e) Case Report: should have an introduction with a brief literature review, a description of the case showing significant results for the diagnosis and differential diagnoses (if any), discussion or comments and references. It should not exceed 1800 words, two tables, illustrations and photographs, up to four authors and a maximum of ten references: f) Letters to the Editor: a maximum of 1000 words (including references), three authors, and two illustrations: g) Images in Clinical Hematology: Maximum 100 words, three authors and three references: h) Scientific comments: will only be accepted by invitation of the editors.

4 Acknowledgements: Should be addressed to collaborators who deserve recognition, but whose participation does not justify their inclusion as an author such as technical assistants, as well as financial support received.

5. References: Use Vancouver style in all categories of articles, the citations must be numeric and inserted according to the order of entry in the text.

Examples of references:

Printed documents

Journals: Padley DJ, Dietz AB, Gastineau DA. Sterility testing of hematopoietic progenitor cell products: a single-institution series of culture-positive rates and successful infusion of culture-positive products. Transfusion. 2007;47(4):636-43.

Books: Chalmers J. Clinician’s manual on blood pressure and stroke prevention. 3rd ed. London: Science Press; 2002. 70 p.

Richardson MD, Warnock DW. Fungal Infection Diagnosis and Management. 2nd ed. Oxford: Blackwell Science Ltd Editorial Offices; 1997.249 p.

Book chapters: F. Reyes. Lymphocyte differentiation. In P Solal-Céligny, N Brousse, F Reyes, C Gisselbrecht, B Coiffier. Non-Hodgkin`s Lymphomas. Paris: Éditions Frison-Roche; 1993. p.19-29.

Annals: Souza AM, Vaz RS, Carvalho MB, Arai Y, Hamerschilak N. Prevalência de testes sorológicos relacionados à hepatitis B e não-A, não-B em doadores de sangue. In: 19º Congresso Brasileiro de Hematologia e Hemoterapia / 26º Congresso da Sociedade Brasileira de Hematologia e Hemoterapia; 2003 Ago 6-9; São Paulo, 2003. Anais. p.103.

Theses: Sandes AF. Caracterização imunofenotípica da diferenciação eritrocitária, granulocítica e megacariótica em pacientes com síndromes mielodisplásicas [thesis]. São Paulo: Universidade Federal de São Paulo; 2009. 126p.

Electronic documents

Articles in Periodicals: Almeida ID, Coitinho AS, Juckowsky CA, Schmalfuss T, Balsan AM, Röhsig LM. Controle de esterilidade de produtos de células progenitoras hematopoéticas do sangue periférico. Rev Bras Hematol Hemoter [Internet] 2010 [cited 2010 Jun 10]; 32(1):23-8. Available from: www.scielo.br/pdf/rbhh/v32n1/aop03010.pdf

Books: Walker HK, Hall WD, Hurst JW, editors. Clinical methods. The history, physical, and laboratory examinations. 3rd ed. [Internet]. Boston: Butterworths; 1990. [cited 2010 Jun 10]. Available from: http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=cm

Illustrations and photos: Must have a resolution of at least 1000 dpi. Color figures should be in CMYK and will be published in color only if essential and must be in TIFF, JPEG or CDR format. Do not send the figures within the text.

Tables: should be numbered consecutively using Arabic numerals and cited in the text in numerical order.

Submission

The submission of the manuscript must be via the website of the Hematology, Transfusion and Cell Therapy, www.scielo.br/revistas/rbhh/www.rbhh.org or https://ees.elsevier.com/htct

When a manuscript is accepted for publication, the author(s) will be requested to complete a conflict of interest form which must be sent to the editorial office.

It is the responsibility of authors to obtain written permission to reproduce any previously published data included in the manuscript.

The editors can publish papers that do not exactly follow the instructions after careful evaluation always taking into account the interests of the readership.

Correspondence address:

Fernando Ferreira Costa
Rua Dr. Diogo de Faria, 775/ conj. 114 – Vila Clementino
São Paulo/SP
CEP: 04037-002
Telephones: (11) 2369-7767 / (11) 2338-6764 www.scielo.br/revistas/rbhh/abhh@abhh.org

There is no fee for submission and evaluation articles.