Open-access Exuberant Vasospastic Angina Simulating Severe Three-Vessel Disease

Keywords:
Angina, Stable / complications; Coronary Vasoespasm; Acute Coronary Syndrome; Coronary Angiography

Palavras-chave:
Angina Estável / complicações; Vasoespasmo Coronário; Síndrome Coronariana Aguda; Angiografia Coronária

Keywords:
Angina, Stable / complications; Coronary Vasoespasm; Acute Coronary Syndrome; Coronary Angiography

Palavras-chave:
Angina Estável / complicações; Vasoespasmo Coronário; Síndrome Coronariana Aguda; Angiografia Coronária

A 56-year-old Caucasian male, came to our hospital complaining of thoracic oppression at exertion and sometimes occurring at rest, lasting for a few minutes. The patient was an active smoker, with a moderate alcohol consumption habit and had had an episode of unstable angina two months earlier. At that episode, two drug-eluting stents were implanted, one in the distal anterior descending artery and the other in the proximal first diagonal artery. The ECG showed mild ST-elevation in V1-V3 and a T-wave inversion in V3-V5. There was a slight increase in Troponin I up to 0.24 ng/mL but the blood tests were otherwise unremarkable. The patient was admitted at the coronary unit and was scheduled for urgent coronary angiogram. The exam revealed severe and diffuse stenosis in the territories of the right and left coronary arteries with slow flow (TIMI 1-2), sparing only the stented segments (picture/video 1). The administration of 2 mg of intracoronary isosorbite dinitrate reverted all the stenosis but slow flow (TIMI 2) was still observed in the left coronary artery. Hence, the diagnosis of vasospastic angina was made. The patient was successfully controlled with calcium antagonists and has remained asymptomatic.

Vasospastic angina is commonly misinterpreted as acute coronary syndrome. Although its pathophysiology is not fully understood, it usually has a favorable long-term prognosis, although coronary artery spasms may have an important role in arrhythmia generation and subsequent cardiac arrest.

Figure 1
Left and right coronary angiogram showing multiple severe stenosis and slow flow.

Video 1
Left and right coronary angiogram showing multiple severe stenosis and slow flow followed by administration of intracoronary isosorbide dinitrate and stenosis resolution. Access the video through the link: http://www.arquivosonline.com.br/2017/english/10806/video_ing.asp

Supported by

Sources of Funding
There were no external funding sources for this study.

Study Association
This study is not associated with any thesis or dissertation work.

Correspondence

Mailing Address: Bruno Marmelo, Av. Rei Dom Duarte. 3500, Viseu - Portugal. E-mail: brunomarmelo@gmail.com

Author contributions

Author contributions
Acquisition of data: Marmelo B; Writing of the manuscript: Marmelo B, Abreu L, Pereira J; Critical revision of the manuscript for intellectual content: Ferreira P, Cabral J.

Conflicts of interest

Potential Conflict of Interest
No potential conflict of interest relevant to this article was reported.

Publication Dates

  • Publication in this collection
    June 2017

History

  • Received
    26 Sept 2016
  • Reviewed
    24 Oct 2016
  • Accepted
    24 Oct 2016
location_on
Sociedade Brasileira de Cardiologia - SBC Avenida Marechal Câmara, 160, sala: 330, Centro, CEP: 20020-907, (21) 3478-2700 - Rio de Janeiro - RJ - Brazil, Fax: +55 21 3478-2770 - São Paulo - SP - Brazil
E-mail: revista@cardiol.br
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