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Anais da Academia Brasileira de Ciências

Print version ISSN 0001-3765

Abstract

NOGAROTO, VIVIANE et al. High Postprandial Triglycerides Serum Levels: Is Obesity a Good Predictor?. An. Acad. Bras. Ciênc. [online]. 2015, vol.87, n.1, pp.437-445.  Epub Feb 03, 2015. ISSN 0001-3765.  http://dx.doi.org/10.1590/0001-3765201520130380.

The aim of this study was to analyze the correlation between triglyceride (TG) serum levels in obese and non-obese patients in a simulated postprandial state. Both groups showed TG levels < 150 mg/dL when fasting. After 12 h fasting, the subjects ingested a lipid overload diet and blood samples were collected. The variation between fasting and the postprandial TG peak levels were analyzed. The peak of postprandial TG levels occurred 4 h after the lipid overload in both groups. When the subjects were not fasting, the majority of non-obese subjects remained within the range of normal TG values, but the values for the obese group remained elevated. There was a significant correlation between Body Mass Index (BMI) and TG at each time point until 2 h after the meal, but the data did not show a correlation after 3 h. According to the receiver-operating characteristics (ROC) curve, postprandial TG values were not a good predictor of obesity (based on BMI), but they were a predictor of non-obesity. This study reinforces the importance of measuring non-fasting TG levels in obese and non-obese subjects, because some non-obese patients probably had altered fat metabolism, indicating that this examination could be an indicator of metabolic risk.

Keywords : body mass index; lipid metabolism; risk factor; ROC curve.

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