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Arquivos Brasileiros de Oftalmologia

Print version ISSN 0004-2749On-line version ISSN 1678-2925


OLIVEIRA, Adália Dias Dourado et al. Correlation between clinical and laboratory findings of infectious corneal ulcer. Arq. Bras. Oftalmol. [online]. 2002, vol.65, n.4, pp.431-439. ISSN 1678-2925.

Purpose: To evaluate the initial treatment of infectious corneal ulcers and their laboratory tests. Methods: Twenty four cases of infectious corneal ulcers seen in the External Corneal Disease Section at the Hospital do Servidor Público Estadual - São Paulo - Brazil, underwent Gram staining and culture for bacterial and fungus. Treatment with fortified cefalotine (50 mg/ml) and gentamicin (14 mg/ml) was started. Results: Seventeen cultures (70.83%) were positive for bacterial infection and seven (29.17%) showed no growth. In three cases (15.76%) the Gram staining showed correlation with the culture. Three cases did not respond to the initial treatment and had the medications changed according to the results of the cultures. All patients responded to the clinical treatment. Conclusions: Ours results showed that combination of fortified cefalotine and gentamicin eye drops was efficient to treat most of the infectious corneal ulcers.

Keywords : Corneal ulcers [drug therapy]; Cephalothin [therapeutic use]; Gentamicins [therapeutic use]; Ciprofloxacin [therapeutic use]; Microbial sensitivity tests; Microbial drug resistance.

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