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Revista do Instituto de Medicina Tropical de São Paulo

versión On-line ISSN 1678-9946

Resumen

STRAUSS, Edna; SAEZ-ALQUEZAR, Amadeo; TAKEDA, Augusta  y  SILVA, Luiz Caetano da. Acute Hepatitis B in a patient previously positive for antibody to surface antigen (anti-HBs) determined by radioimmunoassay: case report and review of the literature. Rev. Inst. Med. trop. S. Paulo [online]. 1985, vol.27, n.5, pp.258-263. ISSN 1678-9946.  https://doi.org/10.1590/S0036-46651985000500005.

The determination of anti-HBs as a screening test before vaccination has been advisable in order to encounter immune individuals that don't need to receive vaccine protection. A case-report is presented and three other cases are reviewed from the literature. Anti-HBs was positive in these health-care personnels that developped typical acute B hepatitis. Different subtyping involving the d/y determinants were found in the first case, but false-positive anti-HBs even with high titres, determined by RIA, were found in the other cases. Concomitant determination of anti-HBc or absence of screening tests seem to be more reasonable policies until a low-cost and risk-free vaccine is produced.

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