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vol.37 suppl.2Prevalence of hepatitis B virus genotypes and the occurrence of precore mutation A-1896 and to correlate them with the clinical presentation of chronic hepatitis, in a population group of the eastern Amazon regionHepatitis B and C virus infection and the hepatocellular carcinoma in the east Amazon, Brazil author indexsubject indexarticles search
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Revista da Sociedade Brasileira de Medicina Tropical

Print version ISSN 0037-8682


MONTEIRO, Maria Rita de Cassia Costa; NASCIMENTO, Margarida Maria Passeri do; PASSOS, Afonso Dinis Costa  and  FIGUEIREDO, José Fernando de Castro. Hepatitis C: prevalence and risk factors among patients with HIV/AIDS in Belém Pará, in Brazilian Amazon. Rev. Soc. Bras. Med. Trop. [online]. 2004, vol.37, suppl.2, pp.40-46. ISSN 0037-8682.

The objective of this investigation was to study the prevalence of hepatitis C virus infection and to identify possible risk factors for its transmission, in 406 adult patients with HIV/Aids who attended at public health services, in Belém city, Pará, Brazil. The anti-HCV was performed by third generation immunoenzymatic technique, and the HCV RNA by polymerase chain reaction. The overall prevalence of hepatitis C virus was 16% (CI: 12.4 - 19.6). Multivariate analysis showed association between virus C infection and age, with significant risk in the group about fifty years old or more (OR=9.75), blood transfusion (OR=4.74) and use of injecting drugs (OR=149.28). The hepatitis C virus infection was detected in 83.7% of intravenous drug users and 22.1% of transfused patients. These data indicate the efficient transmission of the virus through the percutaneous exposition and reaffirm the high risk to hepatitis C among injectable illicit drug user.

Keywords : Hepatitis C; Epidemiology; HIV/Aids; Risk factors; Brazilian amazon.

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