SciELO - Scientific Electronic Library Online

 
vol.34 número2Associação de insegurança alimentar e nutricional com fatores de risco cardiometabólicos na infância e adolescência: uma revisão sistemáticaApresentação atípica de sequestro pulmonar extralobar intra-abdominal detectado no pré-natal: relato de caso índice de autoresíndice de assuntospesquisa de artigos
Home Pagelista alfabética de periódicos  

Serviços Personalizados

Journal

Artigo

Indicadores

Links relacionados

Compartilhar


Revista Paulista de Pediatria

versão impressa ISSN 0103-0582versão On-line ISSN 1984-0462

Resumo

ANDRADE, Maria Izabel Siqueira de et al. Identification of cutoff points for Homeostatic Model Assessment for Insulin Resistance index in adolescents: systematic review. Rev. paul. pediatr. [online]. 2016, vol.34, n.2, pp.234-242. ISSN 1984-0462.  https://doi.org/10.1016/j.rppede.2016.01.004.

Objective:

To identify cutoff points of the Homeostatic Model Assessment for Insulin Resistance (HOMA-IR) index established for adolescents and discuss their applicability for the diagnosis of insulin resistance in Brazilian adolescents.

Data source:

A systematic review was performed in the PubMed, Lilacs and SciELO databases, using the following descriptors: "adolescents", "insulin resistance" and "Receiver Operating Characteristics Curve". Original articles carried out with adolescents published between 2005 and 2015 in Portuguese, English or Spanish languages, which included the statistical analysis using Receiver Operating Characteristics Curve to determine the index cutoff (HOMA-IR) were included.

Data synthesis:

A total of 184 articles were identified and after the study phases were applied, seven articles were selected for the review. All selected studies established their cutoffs using a Receiver Operating Characteristics Curve, with the lowest observed cutoff of 1.65 for girls and 1.95 for boys and the highest of 3.82 for girls and 5.22 for boys. Of the studies analyzed, one proposed external validity, recommending the use of the HOMA-IR cutoff>2.5 for both genders.

Conclusions:

The HOMA-IR index constitutes a reliable method for the detection of insulin resistance in adolescents, as long as it uses cutoffs that are more adequate for the reality of the study population, allowing early diagnosis of insulin resistance and enabling multidisciplinary interventions aiming at health promotion of this population.

Palavras-chave : Insulin resistance; Adolescent; ROC curve; Review.

        · resumo em Português     · texto em Português | Inglês     · Português ( pdf ) | Inglês ( pdf )