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vol.38STATURE ESTIMATE OF CHILDREN WITH CEREBRAL PALSY THROUGH SEGMENTAL MEASURES: A SYSTEMATIC REVIEWNEUROMUSCULAR FITNESS IN EARLY LIFE AND ITS IMPACT ON BONE HEALTH IN ADULTHOOD: A SYSTEMATIC REVIEW author indexsubject indexarticles search
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Revista Paulista de Pediatria

Print version ISSN 0103-0582On-line version ISSN 1984-0462

Abstract

SENA, Berilany dos Santos et al. OVERWEIGHT AND ASSOCIATED FACTORS IN CHILDREN AND ADOLESCENTS WITH PHENYLKETONURIA: A SYSTEMATIC REVIEW. Rev. paul. pediatr. [online]. 2020, vol.38, e2018201.  Epub Mar 09, 2020. ISSN 1984-0462.  http://dx.doi.org/10.1590/1984-0462/2020/38/2018201.

Objective:

To verify the occurrence of overweight in children and adolescents with phenylketonuria and to identify possible causal factors.

Data sources:

A systematic review was performed in the SciELO, PubMed and VHL databases using the descriptors “Phenylketonurias”, “Overweight”, “Child” and “Adolescent”. Original articles conducted with children and adolescents, published between 2008 and 2018 in Portuguese, English or Spanish languages were included.

Data synthesis:

A total of 16 articles were identified and, after screening procedures, 6 studies were selected for the review. Overweight in children and adolescents with phenylketonuria was a frequent occurence in the studies included in this review, ranging from 7.8 to 32.6%. The female sex was the most affected by the nutritional disorder. Furthermore, a high caloric intake combined with a lack of stimuli to practice physical activities were main factors associated with the excessive weight in the population of interest.

Conclusions:

Excess weight can be considered a common outcome in children and adolescents with phenylketonuria. It is mainly caused by inadequate food consumption and sedentary lifestyle. The importance of early identification of nutritional disturbances in children and adolescents with phenylketonuria should be emphasized, in order to prevent associated chronic diseases and to promote health by encouraging continued healthy eating habits and the regular practice of physical exercises.

Keywords : Phenylketonurias; Overweight; Child, Adolescent; Review.

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