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Estudos de Psicologia (Campinas)

versão impressa ISSN 0103-166X

Resumo

KALIL, Rosângela Souza; ALVARENGA, Regina Maria Papais; ALMEIDA, Adilson José de  e  MORAIS-DE-SA, Carlos Alberto. Study of cognitive dysfunction in HIV-1 infected patients. Estud. psicol. (Campinas) [online]. 2009, vol.26, n.4, pp.465-473. ISSN 0103-166X.  https://doi.org/10.1590/S0103-166X2009000400007.

In its early stages, HIV-1 infection involves the Central Nervous System causing neuropsychological manifestations. With the aim of studying the cognitive functions in HIV-1-infected patients, a total of 20 patients infected with HIV-1 with CD4+ lymphocyte count >200 cells/mm3 were studied in accordance with the Wechsler Adult Intelligence Scale (WAIS-III). The present study comprised 20 patients, 5 (25%) male and 15 (75%) female, with a mean age of 39.65 and standard deviation of 10.15 years. The mean CD4+ lymphocyte count was 467.20 with a standard deviation of 215.45 cells/mm3. Amongst the 14 patients who received highly active anti-retroviral therapy (HAART), we noted 1 case in which the performance of the cognitive functions, attention span and learning, was considered to be very low according to WAIS-III, and the remaining (n=13) patients who were treated with HAART demonstrated a performance that was not considered to be outside of the WAIS-III mean. By using WAIS-III testing, it was possible to detect performance of the cognitive functions considered to be very low in HIV-1 infected individuals, even with those receiving HAART.

Palavras-chave : Neuropsychological assessment; Human-immunodeficiency-virus; Cognition disorders.

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