SciELO - Scientific Electronic Library Online

vol.25 issue2Perceptions and practices regarding delirium, sedation and analgesia in critically ill patients: a narrative reviewUse of femoral vein catheters for the assessment of perfusion parameters author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand




Related links


Revista Brasileira de Terapia Intensiva

Print version ISSN 0103-507X


HELDT, Tatiane  and  LOSS, Sergio Henrique. Drug-nutrient interactions in the intensive care unit: literature review and current recommendations. Rev. bras. ter. intensiva [online]. 2013, vol.25, n.2, pp.162-167. ISSN 0103-507X.

OBJECTIVE: To describe the interactions between drugs and nutrients and their frequency in the intensive care unit and to assess the professional team's awareness regarding this subject. METHODS: The keywords "drug interactions" and "nutrition therapy" were searched in the PubMed (specifically MeSH) electronic database. The studies were systematically reviewed for descriptions of the types of interactions between drugs and nutrients, including their frequency and consequences. RESULTS: Sixty-seven articles were found. Among these, 20 articles were appropriate for the methodology adopted and accomplished the objectives of the study. Of these 20 articles, 14 articles described interactions between drugs and enteral nutrition, three described interactions between drugs and parenteral nutrition, and three described the importance and care required to avoid such interactions. CONCLUSIONS: The literature about drug and nutrient interactions is limited and suggests the inability of health care teams to recognize the potential for these interactions. Possibly, the elaboration of a protocol to evaluate drug-nutrient interactions will increase the safety and efficacy of therapeutics.

Keywords : Pharmaceutical preparations; Nutrients; Nutrition therapy; Intensive care; Critical care; Drug interactions.

        · abstract in Portuguese     · text in Portuguese     · English ( pdf ) | Portuguese ( pdf )


Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License