SciELO - Scientific Electronic Library Online

 
vol.31 número1Escala Perme como preditor de funcionalidade e complicações após a alta da unidade de terapia intensiva em pacientes submetidos a transplante hepáticoCaracterísticas e desfechos de pacientes com sepse adquirida na comunidade e no hospital índice de autoresíndice de assuntospesquisa de artigos
Home Pagelista alfabética de periódicos  

Serviços Personalizados

Journal

Artigo

Indicadores

Links relacionados

Compartilhar


Revista Brasileira de Terapia Intensiva

versão impressa ISSN 0103-507Xversão On-line ISSN 1982-4335

Resumo

MARTINS, Eduarda Cristina et al. Neutrophil-lymphocyte ratio in the early diagnosis of sepsis in an intensive care unit: a case-control study. Rev. bras. ter. intensiva [online]. 2019, vol.31, n.1, pp.64-70.  Epub 21-Mar-2019. ISSN 1982-4335.  https://doi.org/10.5935/0103-507x.20190010.

Objective:

To evaluate the neutrophil-lymphocyte ratio as a predictor of sepsis and mortality in patients admitted to an intensive care unit.

Methods:

Case-control study of adult patients admitted to an intensive care unit. Patients who had sepsis as the reason for admission and who had a previous complete blood count examination were included as case patients. The following statistical analyses were performed: ROC curves, binary logistic regression, and Mann-Whitney and Pearson's chi-square tests. p < 0.05 was considered significant.

Results:

The ROC curve values were 0.62 for neutrophil-lymphocyte ratio, 0.98 for band neutrophils and 0.51 for total leukocytes. The presence of a neutrophil-lymphocyte ratio greater than 5.0, leukocyte count above 12,000mm3/mL and band neutrophil percentage above 10% were risk factors for sepsis; however, only the SAPS 3 and SOFA score were related to patient mortality.

Conclusion:

The neutrophil-lymphocyte ratio and band neutrophils in combination with other parameters may be markers for the early detection of sepsis in intensive care units.

Palavras-chave : Sepsis/diagnosis; Blood cell count; Clinical laboratory techniques; Lymphocyte count/methods; Neutrophils; Intensive care units.

        · resumo em Português     · texto em Português | Inglês     · Português ( pdf ) | Inglês ( pdf )