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Anais Brasileiros de Dermatologia

versão impressa ISSN 0365-0596versão On-line ISSN 1806-4841

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BARROSO, Livia Ariane Lopes; STERNBERG, Flavia; SOUZA, Maria Natalia Inacio de Fraia e  e  NUNES, Gisele Jacobino de Barros. Trichotillomania: a good response to treatment with N-acetylcysteine. An. Bras. Dermatol. [online]. 2017, vol.92, n.4, pp.537-539. ISSN 1806-4841.  https://doi.org/10.1590/abd1806-4841.20175435.

Trichotillomania is considered a behavioral disorder and is characterized by the recurring habit of pulling one's hair, resulting in secondary alopecia. It affects 1% of the adult population, and 2 to 4.4% of psychiatric patients meet the diagnostic criteria. It can occur at any age and is more prevalent in adolescents and females. Its occurrence in childhood is not uncommon and tends to have a more favorable clinical course. The scalp, eyebrows and eyelashes are the most commonly affected sites. Glutamate modulating agents, such as N-acetylcysteine, have been shown to be a promising treatment. N-acetylcysteine acts by reducing oxidative stress and normalizing glutaminergic transmission. In this paper, we report a case of trichotillomania with an excellent response to N-acetylcysteine.

Palavras-chave : Acetylcysteine; Alopecia; Glutamates; Trichotillomania.

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