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vol.32 suppl.2Differential diagnosis of iron deficiencyIron deficiency in infants and children author indexsubject indexarticles search
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Revista Brasileira de Hematologia e Hemoterapia

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CHOPARD, Maria Renata T.; MAGALHAES, Maurício  and  BRUNIERA, Paula. Iron deficiency in the fetus and newborn. Rev. Bras. Hematol. Hemoter. [online]. 2010, vol.32, suppl.2, pp.32-37.  Epub May 28, 2010. ISSN 1516-8484.

The main cause of anemia in the fetus is hemolytic disease. Mildly anemic pregnant women may evolve with premature labor and have low birth weight babies, but the baby's iron status is not influenced by the mother's iron deficiency. Iron transportation through the placenta occurs in the third trimester of gestation and premature labor results in reduced iron stores. Iron deficiency anemia does not occur during the neonatal period, but premature and low birth weight babies are at risk of developing iron deficiency. In full-term babies iron deficiency can occur due to intestinal malformation that leads to duodenal resection. To avoid iron deficiency in at-risk babies, iron supplementation is recommended from the thirtieth postnatal day. The best method to avoid iron absorption deficiency in premature babies is the enteral administration of iron. Iron polymaltose complex and amino acid-based iron chelators are preferable to ferrous sulfate in premature babies because of the reduced oxidative side effects of iron administration. Intravenous administration is safe and does not increase the oxidative side effects.

Keywords : Anemia; iron deficiency; iron; fetus; newborn.

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