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Revista Brasileira de Medicina do Esporte

Print version ISSN 1517-8692On-line version ISSN 1806-9940


LEANDRO, Carol Góis et al. Adaptative mechanisms of the immune system in response to physical training. Rev Bras Med Esporte [online]. 2007, vol.13, n.5, pp.343-348. ISSN 1806-9940.

Moderate physical training enhances the defense mechanisms, while intense physical training induces to immune suppression. The underlying mechanisms are associated with the link between nervous, endocrine, and immune systems. It suggests autonomic patterns and modulation of immune response. Immune cells, when exposed to regular bouts of stress, develop a mechanism of tolerance. In many tissues, it has been demonstrated that the response to aggressive conditions is attenuated by moderate physical training. Thus, training can induce tolerance to aggressive/stressful situations. In this review, studies suggesting the adaptation mechanisms of the immune system in response to physical training will be reported.

Keywords : Physical exercise; Cross-tolerance; Leukocytes.

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