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KRAYCHETE, Durval Campos; GARCIA, João Batista Santos; SIQUEIRA, José Tadeu Tesseroli de  and  GRUPO DE ESPECIALISTAS. Recommendations for the use of opioids in Brazil: Part IV. Adverse opioid effects. Rev. dor [online]. 2014, vol.15, n.3, pp.215-223. ISSN 1806-0013.


Adequate opioid use in the short and long term, as well as diagnosis, management of adverse effects, abuse and chemical dependence of such agents are still an investigation area for many researchers. This study aimed at discussing actions for monitoring, diagnosing and managing adverse effects common to those drugs.


This article addresses diagnosis and management of common opioid adverse effects, as well as abuse and chemical dependence, discussing the frequency of such alterations, the pharmacological and complementary management, risks associated to therapy and most relevant recommendations.


Several are the effects of acute or chronic opioid administration. A recommended strategy is to monitor, diagnose the occurrence and adequately treat effects so that there is no damage for patients needing such substances, thus preventing therapy interruption.

Keywords : Adverse effects; Opioids.

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