SciELO - Scientific Electronic Library Online

vol.17 issue4Prevalence of opiophobia in cancer pain treatmentPain evaluation in workers of the textile industry author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand




Related links


Revista Dor

Print version ISSN 1806-0013On-line version ISSN 2317-6393


GALVAO-MOREIRA, Leonardo Victor et al. Morning salivary cortisol with regard to gender in individuals with perceived facial pain. Rev. dor [online]. 2016, vol.17, n.4, pp.248-253. ISSN 2317-6393.


Facial pain seems to be related to physiological responses to stress and sexual dimorphism. However, the relationship among facial pain, cortisol secretion and gender has been poorly investigated. This study aimed to investigate differences in morning salivary cortisol profile between males and females either with or without perceived facial pain symptoms.


Participated in the study 39 individuals reporting facial pain and 33 painless controls of both genders. Facial pain symptoms were evaluated with Axis II Research Diagnostic Criteria for Temporomandibular Disorders, which has supplied chronic pain scores. Saliva was collected in the morning to obtain cortisol peaks, being stored for further use. Salivary cortisol levels were evaluated by immunosorbent assay. Statistical analysis has included hypotheses tests and ANOVA with significance level of 5% and a binary logistic regression, which has tested the association between gender, cortisol and each facial pain symptom.


There has been no association between facial pain and gender. Cortisol levels were similar among individuals with and without facial pain, regardless of gender. The adjusted model has shown that most symptoms were not associated to gender, regardless of cortisol levels.


In individuals with and without facial pain symptoms, morning salivary cortisol levels regulation has been similar for both genders.

Keywords : Chronic pain; Comorbidity; Cortisol; Facial pain; Gender; Psychological stress.

        · abstract in Portuguese     · text in English     · English ( pdf )