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Jornal Brasileiro de Pneumologia

On-line version ISSN 1806-3756

Abstract

SOUZA, Rogério; JARDIM, Carlos; SALGE, João Marcos  and  CARVALHO, Carlos Roberto Ribeiro. Smoke inhalation injury. J. bras. pneumol. [online]. 2004, vol.30, n.6, pp.557-565. ISSN 1806-3756.  http://dx.doi.org/10.1590/S1806-37132004000600011.

Inhalation injury is the main cause of death in burn patients and has therefore, understandably, been the subject of numerous published studies. The pathogenesis of inhalation injury involves both local and systemic mechanisms, thereby increasing the repercussions of the injury. The search for tools that would allow earlier diagnosis of inhalation injury and for treatment strategies to lessen its deleterious effects is ongoing. In this review, we describe the physiopathological mechanisms of inhalation injury, as well as the current diagnostic tools and treatment strategies used in patients suffering from inhalation injury. We also attempt to put experimental therapeutic approaches into perspective.

Keywords : Smoke inhalation injury [diagnosis]; Smoke inhalation injury [pathophysiology]; Smoke inhalation injury [complications]; Burns, inhalation [therapy]; Review literature; Carbon monoxide; Poisoning [complications].

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