SciELO - Scientific Electronic Library Online

 
vol.34 número3Methods for quantification of cerebral glycolytic metabolism using 2-deoxy-2-[18 F]fluoroglucose in small animalsMulti-view autostereoscopic system for 3D visualization in anatomy índice de autoresíndice de materiabúsqueda de artículos
Home Pagelista alfabética de revistas  

Servicios Personalizados

Revista

Articulo

Indicadores

Links relacionados

Compartir


Research on Biomedical Engineering

versión impresa ISSN 2446-4732versión On-line ISSN 2446-4740

Resumen

HELL, Alessandra Forgatti et al. Production of fibrous polymer scaffolds for tissue engineering using an automated solution blow spinning system. Res. Biomed. Eng. [online]. 2018, vol.34, n.3, pp.273-278.  Epub 22-Oct-2018. ISSN 2446-4740.  http://dx.doi.org/10.1590/2446-4740.180039.

Introduction

Solution blow spinning (SBS) and airbrushing are two techniques that can be used as alternatives to electrospinning in the production of fibrous scaffolds for tissue engineering (TE). SBS seems particularly interesting due to its versatility, however, it has not been much explored and no automated SBS systems were found in the literature. Therefore, the present work aimed to develop such equipment and compare the results to those found for airbrushing, considering the same set of parameters.

Methods

A new SBS set up, composed of a specially designed nozzle with automated movement, a syringe pump and a compressor, was used to produce fibrous poly (ε-caprolactone) (PCL) mats. The airbrushed fibers were produced under the same conditions, and samples of both types of mats were imaged using scanning electron microscopy (SEM) to compare them in terms of microstructure and fiber diameter.

Results

The SBS system was robust and performed well, in terms of movement and fiber deposition. In comparison to airbrushing’s, SBS mats presented different microstructural characteristics (considering the parameters used).

Conclusion

The biggest advantage over airbrushing may be its versatility and simple automation, which may improve sample reproducibility, especially considering scaled up processes. To further improve this apparatus, a better understanding of how process variables interfere in the microstructure is needed, as well as more sophisticated interface and operation.

Palabras clave : Fibrous scaffolds; Solution blow spinning; Airbrushing.

        · texto en Inglés     · Inglés ( pdf )