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Arquivos de Neuro-Psiquiatria

Print version ISSN 0004-282X

Arq. Neuro-Psiquiatr. vol.43 no.2 São Paulo June 1985

https://doi.org/10.1590/S0004-282X1985000200006 

Proteína básica de mielina no líquido cefalorraqueano na neurocisticercose

 

Myelin basic protein in cerebrospinal fluid of patients with neurocysticercosis

 

 

J. A. LivramentoI; L. R. MachadoI; J. N. WhitakerII; A. Spina-FrançaIII

IMédico Assistente. Centro de Investigações em Neurologia da Faculdade de Medicina da Universidade de São Paulo (FMUSP) e do Department of Neurology, Center for the Health Sciences, University of Tennessee, Memphis, USA (CHSUT)
IIProfessor of Neurology and Chairman (CHSUT)
IIIProfessor Titular de Neurologia (FMUSP)

 

 


RESUMO

Foram estudadas 133 amostras de LCR provenientes de 115 pacientes para verificar o teor da PBM, fragmento P1 43-88. Os casos foram subdivididos em subgrupos de acordo com o diagnóstico nosológico. No grupo controle (50 casos de pacientes com cefaléia crônica) não houve detecção de PBM em qualquer das amostras; dos casos de neurocisticercose (44), em 4 havia presença da PBM; nos de esclerose múltipla (8) em três havia PBM; em um caso de neuroes-quistossomose, forma medular, também foi detectada a presença da PBM. Considerações de ordem neuroimunológica são tecidas sobre os resultados encontrados.


SUMMARY

Cerebrospinal fluid (CSF) from 115 patients with several neurological disorders were tested for the presence of myelin basic protein (MBP), fragment P1 43-88. Cases were divided into groups according to neurological diagnosis. The control group (50 patients with chronic headache) presented normal CSF composition and presented no evidence of the presence of MBP. MBP was found in: four cases of the 44 of neurocysticercosis; three of the 8 cases of multiple sclerosis; one case of schistosomiasis with spinal cord involvement. Neuroimmunological data are discussed considering results found in this investigation.


 

 

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Trabalho do Centro de Investigações em Neurologia da Faculdade de Medicina da Universidade de São Paulo (FMUSP) e do Department of Neurology, Center for the Health Sciences, University of Tennessee, Memphis, USA (CHSUT).
Centro de Investigações em Neurologia, FMUSP - Caixa Postal 5199 - 01000, São Paulo, SP - Brasil.

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