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Arquivos de Neuro-Psiquiatria

Print version ISSN 0004-282X

Arq. Neuro-Psiquiatr. vol.51 no.4 São Paulo Nov. 1993 

Arachnoid granulation affected by subarachnoid hemorrhage


Estudo das componentes fibrosas das granulações aracnóides na presença de hemorragia sub-aracnóide



R.P. ChopardI; R.C. BrancalhãoII; M.H. Miranda-NetoIII; W. BiazottoIII

IDepartamento de Anatomia, Instituto de Ciências Biológicas (ICB), Universidade de São Paulo (USP)
IIUNIOESTE, Cascavel, Paraná
IIIUniversidade Estadual de Maringá, Paraná




The purpose of this study was to investigate using light microscopy the fibro-cellular components of arachnoid granulations affected by mild and severe subarachnoid hemorrage. The erythrocytes were in the channels delimitated by collagenous and elastic bundles and arachnoid cells, showing their tortuous and intercommunicating row from the pedicle to the fibrous capsule. The core portion of the pedicle and the center represented a principal route to the bulk outflow of cerebrospinal fluid and erythrocytes. In the severe hemorrhage, the fibrocellular components are desorganized, increasing the extracellular channels. We could see arachnoid granulations without erythrocytes, which cells showed big round nucleous suggesting their transformation into phagocytic cells.

Key words: arachnoid granulation, subarachnoid hemorrhage, cerebrospinal fluid.


Por microscopia óptica foram estudados os componentes fibrosos das granulações aracnóides de indivíduos acometidos por hemorragia subaracnóide de tipo moderado ou severo. Os eritrocitos estavam presentes nos canais delimitados por feixes de fibras elásticas, colágenas e células aracnóides. Os canais tortuosos e intercomunicantes eram observados desde o pedículo até a cápsula fibrosa da granulação aracnóide. O principal trajeto dos eritrócitos e do líquido céfalo-raquidiano ocorria no interior do pedículo e centro da granulação aracnóide. Na hemorragia severa, os componentes fibro-musculares estavam desorganizados e os canais extra-celulares aumentados. A presença de células com grandes núcleos, observada no material hemorrágico, é sugestiva de transformações das células aracnóides em células fagocitárias, para promover a digestão intracelular dos eritrocitos.

Palavras-chave: granulação aracnóide, hemorragia subaracnóide, líquido cefalorra-quidiano.



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Aceite: 30-março-1993.



Dr. Renato P. Chopard — Departamento de Anatomia - Faculdade de Medicina, USP - Av. Dr. Arnaldo 455 - 01246-000 São Paulo SP - Brasil.

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