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Arquivos de Neuro-Psiquiatria

Print version ISSN 0004-282X

Arq. Neuro-Psiquiatr. vol.52 no.4 São Paulo Dec. 1994

http://dx.doi.org/10.1590/S0004-282X1994000400016 

Acidóse tubular renal distal manifestando-se com rabdomiólise

 

Distail renal tubular acidosis manifesting with rhabdomyolysis

 

 

Edmar ZanoteliI; Acary Souza Bulle de OliveiraI; Célia Harumi TenganI; Maria da Penha Ananias MoritaI; Beny SchmidtII; Alberto Alain GabbaiI

IDisciplina de Neurologia, Departamento de Neurologia, Neurocirurgia e Neurologia Experimental, Escola Paulista de Medicina (EPM)
IIDepartamento de Anatomia Patológica, EPM

 

 


RESUMO

A hipocalemia severa é causa incomum de rabdomiólise. Descreve-se o caso de urna paciente de 28 anos com acidóse tubular renal distal, que desenvolveu hipocalemia severa com consequente rabdomiólise. O estudo histológico do músculo evidenciou áreas focais de necrose muscular predominando em fibras do tipo II, com discreta reação macrofágica. A melhora clínica e laboratorial apresentada pela paciente ocorreu após a normalização do potássio sérico, tendo sido fundamental, neste caso, a correção da acidóse metabólica.

Palavras-chave: hipocalemia, rabdomiólise, acidóse tubular renal.


SUMMARY

Severe hypokalemia is an uncommon cause of rhabdomyolysis. We describe a patient, 28-year-old woman, with distal renal tubular acidosis (DRTA) who developed severe hypokalemia and rhabdomyolysis. Muscle biopsy shows focal muscular necrosis mainly in type II muscle fibers and mild macrophagic reaction. After correcting the acidosis with oral administration of alkalinizing salts, clinical and laboratory improvement was seen. This clearly establish a causal realtionship between the positive acid balance, hypokalemia and the muscular manifestation in DRTA.

Key words: hypokalemia, rhabdomyolysis, renal tubular acidosis.


 

 

Texto completo disponível apenas em PDF.

Full text available only in PDF format.

 

 

Agradecimentos - Agradecemos ao Prof. Dr. Nestor Schor, docente da Disciplina de Nefrologia da Escola Paulista de Medicina, pela prestigiosa colaboração na análise e correção deste estudo.

 

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Aceite: 13-junho-1994.

 

 

Dr. Acary S.B. Oliveira - Disciplina de Neurologia, Escola Paulista de Medicina - Rua Botucatu 740 - 04023-062 São Paulo SP - Brasil.

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